SCOP 1.67: Domain d1omwa3: 1omw A:186-549

Lineage for d1omwa3 (1omw A:186-549)

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (47 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein G-protein coupled receptor kinase 2 [90034] (1 species)
   AGC group; GRKs subfamily; serine/threonine kinase

7. Species Cow (Bos taurus) [TaxId:9913] [90035] (1 PDB entry)

8. Domain d1omwa3: 1omw A:186-549 [87088]
   Other proteins in same PDB: d1omwa1, d1omwa2, d1omwb_, d1omwg_
   complexed with cmt; mutant

Details for d1omwa3

PDB Entry: 1omw, 2.5 Å

PDB Description: crystal structure of the complex between g protein-coupled receptor kinase 2 and heterotrimeric g protein beta 1 and gamma 2 subunits

SCOP Domain Sequences for d1omwa3:

Sequence, based on SEQRES records:

>d1omwa3 d.144.1.7 (A:186-549) G-protein coupled receptor kinase 2 {Cow (Bos taurus)}
ltmndfsvhriigrggfgevygcrkadtgkmyamkcldkkrikmkqgetlalnerimlsl
vstgdcpfivcmsyafhtpdklsfildlmnggdlhyhlsqhgvfseadmrfyaaeiilgl
ehmhnrfvvyrdlkpanilldehghvrisdlglacdfskkkphasvgthgymapevlqkg
vaydssadwfslgcmlfkllrghspfrqhktkdkheidrmtltmavelpdsfspelrsll
egllqrdvnrrlgclgrgaqevkespffrsldwqmvflqkyppplipprgevnaadafdi
gsfdeedtkgiklldsdqelyrnfpltiserwqqevaetvfdtinaetdrlearkktknk
qlgh

Sequence, based on observed residues (ATOM records):

>d1omwa3 d.144.1.7 (A:186-549) G-protein coupled receptor kinase 2 {Cow (Bos taurus)}
ltmndfsvhriigrggfgevygcrkadtgkmyamkcldkkrikmkqgetlalnerimlsl
vstgdcpfivcmsyafhtpdklsfildlmnggdlhyhlsqhgvfseadmrfyaaeiilgl
ehmhnrfvvyrdlkpanilldehghvrisdlglacdfskkkphasvgthgymapevlqkg
vaydssadwfslgcmlfkllrghspfrqhktkdkheidrmtltmavelpdsfspelrsll
egllqrdvnrrlgclgrgaqevkespffrsldwqmvflqkyppplipprgiklldsdqel
yrnfpltiserwqqevaetvfdtinaetdrlearkktknkqlgh

Timeline for d1omwa3:

• d1omwa3 first appeared in SCOP 1.65
  
• d1omwa3 appears in SCOP 1.69
  
• d1omwa3 appears in the current release, SCOPe 2.08