Lineage for d1o04a_ (1o04 A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2908566Fold c.82: ALDH-like [53719] (1 superfamily)
    consists of two similar domains with 3 layers (a/b/a) each; duplication
    core: parallel beta-sheet of 5 strands, order 32145
  4. 2908567Superfamily c.82.1: ALDH-like [53720] (3 families) (S)
    binds NAD differently from other NAD(P)-dependent oxidoreductases
  5. 2908568Family c.82.1.1: ALDH-like [53721] (6 proteins)
  6. 2908573Protein Aldehyde reductase (dehydrogenase), ALDH [53722] (9 species)
  7. 2908597Species Human (Homo sapiens), mitochondrial [TaxId:9606] [53726] (27 PDB entries)
    Uniprot P05091
  8. 2908598Domain d1o04a_: 1o04 A: [86508]
    complexed with edo, gai, mg, na, nad; mutant

Details for d1o04a_

PDB Entry: 1o04 (more details), 1.42 Å

PDB Description: cys302ser mutant of human mitochondrial aldehyde dehydrogenase complexed with nad+ and mg2+
PDB Compounds: (A:) Aldehyde dehydrogenase, mitochondrial precursor

SCOPe Domain Sequences for d1o04a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1o04a_ c.82.1.1 (A:) Aldehyde reductase (dehydrogenase), ALDH {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
avpapnqqpevfcnqifinnewhdavsrktfptvnpstgevicqvaegdkedvdkavkaa
raafqlgspwrrmdashrgrllnrladlierdrtylaaletldngkpyvisylvdldmvl
kclryyagwadkyhgktipidgdffsytrhepvgvcgqiipwnfpllmqawklgpalatg
nvvvmkvaeqtpltalyvanlikeagfppgvvnivpgfgptagaaiashedvdkvaftgs
teigrviqvaagssnlkrvtlelggkspniimsdadmdwaveqahfalffnqgqcscags
rtfvqediydefversvaraksrvvgnpfdskteqgpqvdetqfkkilgyintgkqegak
llcgggiaadrgyfiqptvfgdvqdgmtiakeeifgpvmqilkfktieevvgrannstyg
laaavftkdldkanylsqalqagtvwvncydvfgaqspfggykmsgsgrelgeyglqayt
evktvtvkvpqkns

SCOPe Domain Coordinates for d1o04a_:

Click to download the PDB-style file with coordinates for d1o04a_.
(The format of our PDB-style files is described here.)

Timeline for d1o04a_: