Lineage for d1nvws_ (1nvw S:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2338409Fold a.117: Ras GEF [48365] (1 superfamily)
    multihelical
  4. 2338410Superfamily a.117.1: Ras GEF [48366] (1 family) (S)
  5. 2338411Family a.117.1.1: Ras GEF [48367] (2 proteins)
  6. 2338412Protein Son of sevenless protein homolog 1 (sos-1) [48368] (1 species)
  7. 2338413Species Human (Homo sapiens) [TaxId:9606] [48369] (60 PDB entries)
    Uniprot Q07889 189-1046
  8. 2338461Domain d1nvws_: 1nvw S: [86282]
    Other proteins in same PDB: d1nvwq_, d1nvwr_
    complexed with gnp, mg, po4

Details for d1nvws_

PDB Entry: 1nvw (more details), 2.7 Å

PDB Description: Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
PDB Compounds: (S:) Son of sevenless protein homolog 1

SCOPe Domain Sequences for d1nvws_:

Sequence, based on SEQRES records: (download)

>d1nvws_ a.117.1.1 (S:) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
qmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnfvr
tflttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpv
qlrvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiard
ngpghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpselv
gsvwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvfqel
nnfngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinpp
cvpffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrves
dikrffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsnp
r

Sequence, based on observed residues (ATOM records): (download)

>d1nvws_ a.117.1.1 (S:) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
qmrlpsadvyrfaepdseeniifeegipiikagtviklierltyhmyadpnfvrtfltty
rsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpvqlrvln
vcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiahnitfqss
pptvewhisrpghietfdlltlhpieiarqltllesdlyravqpselvgsvwtkedkein
spnllkmirhttnltlwfekcivetenleervavvsriieilqvfqelnnfngvlevvsa
mnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinppcvpffgiyltni
lkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrvesdikrffenlnpm
gnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsnpr

SCOPe Domain Coordinates for d1nvws_:

Click to download the PDB-style file with coordinates for d1nvws_.
(The format of our PDB-style files is described here.)

Timeline for d1nvws_: