Lineage for d1nuoa_ (1nuo A:)

  1. Root: SCOP 1.65
  2. 275720Class a: All alpha proteins [46456] (179 folds)
  3. 285381Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 285382Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family) (S)
  5. 285383Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (25 proteins)
  6. 285575Protein Thyroid hormone receptor beta (TR-beta) [48530] (1 species)
  7. 285576Species Human (Homo sapiens) [TaxId:9606] [48531] (7 PDB entries)
  8. 285583Domain d1nuoa_: 1nuo A: [86198]
    complexed with 4hy; mutant

Details for d1nuoa_

PDB Entry: 1nuo (more details), 3.1 Å

PDB Description: Two RTH Mutants with Impaired Hormone Binding

SCOP Domain Sequences for d1nuoa_:

Sequence, based on SEQRES records: (download)

>d1nuoa_ a.123.1.1 (A:) Thyroid hormone receptor beta (TR-beta) {Human (Homo sapiens)}
meelqksighkpeptdeeweliktvteahvatnaqgshwkqkrkflpddigqapivnape
ggkvdleafshftkiitpaitrvvdfakklpmfcelpcedqiillkgccmeimslhaavr
ydpesetltlngemavtrgqlkngglgvvsdaifdlgmslssfnlddtevallqavllms
sdrpglacveriekyqdsfllafehyinyrkhhvthfwpkllmkvtdlrmigachasrfl
hmkvecptelfpplflevfe

Sequence, based on observed residues (ATOM records): (download)

>d1nuoa_ a.123.1.1 (A:) Thyroid hormone receptor beta (TR-beta) {Human (Homo sapiens)}
meelqksighkpeptdeeweliktvteahvatnagshwkqkrkflpddigqdleafshft
kiitpaitrvvdfakklpmfcelpcedqiillkgccmeimslhaavrydpesetltlnge
mavtrgqlkngglgvvsdaifdlgmslssfnlddtevallqavllmssdrpglacverie
kyqdsfllafehyinyrkhhvthfwpkllmkvtdlrmigachasrflhmkvecptelfpp
lflevfe

SCOP Domain Coordinates for d1nuoa_:

Click to download the PDB-style file with coordinates for d1nuoa_.
(The format of our PDB-style files is described here.)

Timeline for d1nuoa_: