SCOP 1.65: Domain d1nr1d1: 1nr1 D:213-505

Lineage for d1nr1d1 (1nr1 D:213-505)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (10 families)

5. Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (10 proteins)
   extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site

6. Protein Glutamate dehydrogenase [51884] (7 species)

7. Species Human (Homo sapiens) [TaxId:9606] [75115] (2 PDB entries)

8. Domain d1nr1d1: 1nr1 D:213-505 [86086]
   Other proteins in same PDB: d1nr1a2, d1nr1b2, d1nr1c2, d1nr1d2, d1nr1e2, d1nr1f2

Details for d1nr1d1

PDB Entry: 1nr1, 3.3 Å

PDB Description: crystal structure of the r463a mutant of human glutamate dehydrogenase

SCOP Domain Sequences for d1nr1d1:

Sequence; same for both SEQRES and ATOM records:

>d1nr1d1 c.2.1.7 (D:213-505) Glutamate dehydrogenase {Human (Homo sapiens)}
hgrisatgrgvfhgienfineasymsilgmtpgfgdktfvvqgfgnvglhsmrylhrfga
kciavgesdgsiwnpdgidpkeledfklqhgsilgfpkakpyegsileadcdilipaase
kqltksnaprvkakiiaegangpttpeadkiflernimvipdlylnaggvtvsyfewlkn
lnhvsygrltfkyerdsnyhllmsvqeslerkfgkhggtipivptaefqdrisgasekdi
vhsglaytmeasarqimrtamkynlgldlrtaayvnaiekvfkvyneagvtft

Timeline for d1nr1d1:

• d1nr1d1 is new in SCOP 1.65
  
• d1nr1d1 appears in SCOP 1.67
  
• d1nr1d1 appears in the current release, SCOPe 2.08