SCOP 1.69: Domain d1npyb1: 1npy B:103-270

Lineage for d1npyb1 (1npy B:103-270)

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (11 proteins)
   extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site

6. Protein Shikimate 5-dehydrogenase-like protein HI0607 [89536] (1 species)

7. Species Haemophilus influenzae [TaxId:727] [89537] (1 PDB entry)

8. Domain d1npyb1: 1npy B:103-270 [85997]
   Other proteins in same PDB: d1npya2, d1npyb2, d1npyc2, d1npyd2

Details for d1npyb1

PDB Entry: 1npy, 1.75 Å

PDB Description: structure of shikimate 5-dehydrogenase-like protein hi0607

SCOP Domain Sequences for d1npyb1:

Sequence; same for both SEQRES and ATOM records:

>d1npyb1 c.2.1.7 (B:103-270) Shikimate 5-dehydrogenase-like protein HI0607 {Haemophilus influenzae}
dyiaivkliekyhlnknakvivhgsggmakavvaafknsgfeklkiyarnvktgqylaal
ygyayinslenqqadilvnvtsigmkggkeemdlafpkafidnasvafdvvampvetpfi
ryaqargkqtisgaavivlqaveqfelythqrpsdeliaeaaafartk

Timeline for d1npyb1:

• d1npyb1 first appeared in SCOP 1.65
  
• d1npyb1 appears in SCOP 1.67
  
• d1npyb1 appears in SCOP 1.71
  
• d1npyb1 appears in the current release, SCOPe 2.08