SCOPe 2.06: Domain d1npha2: 1nph A:533-628

Lineage for d1npha2 (1nph A:533-628)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.109: Gelsolin-like [55752] (3 superfamilies)
   3 layers: a/b/a; contains mixed beta-sheet

4. Superfamily d.109.1: Actin depolymerizing proteins [55753] (3 families)

5. Family d.109.1.1: Gelsolin-like [55754] (5 proteins)

6. Protein Gelsolin [55759] (2 species)
   consists of six similar domains

7. Species Human (Homo sapiens) [TaxId:9606] [55761] (39 PDB entries)
   Uniprot P20065 55-179

8. Domain d1npha2: 1nph A:533-628 [85957]
   domains 4, 5 and 6 in active, actin free conformation
   complexed with ca

Details for d1npha2

PDB Entry: 1nph, 3 Å

PDB Description: Gelsolin Domains 4-6 in Active, Actin Free Conformation Identifies Sites of Regulatory Calcium Ions

PDB Compounds: (A:) gelsolin

SCOPe Domain Sequences for d1npha2:

Sequence; same for both SEQRES and ATOM records:

>d1npha2 d.109.1.1 (A:533-628) Gelsolin {Human (Homo sapiens) [TaxId: 9606]}
pasirlfqvrasssgatravevmpksgalnsndafvlktpsaaylwvgagaseaektaaq
ellkvlrsqhvqveegsepdgfwealggktsyrtsp

Timeline for d1npha2:

• d1npha2 first appeared in SCOP 1.65
  
• d1npha2 appears in SCOPe 2.05
  
• d1npha2 appears in SCOPe 2.07
  
• d1npha2 appears in the current release, SCOPe 2.08