SCOP 1.67: Domain d1npha1: 1nph A:414-532

Lineage for d1npha1 (1nph A:414-532)

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.109: Gelsolin-like [55752] (2 superfamilies)
   3 layers: a/b/a; contains mixed beta-sheet

4. Superfamily d.109.1: Actin depolymerizing proteins [55753] (2 families)

5. Family d.109.1.1: Gelsolin-like [55754] (4 proteins)

6. Protein Gelsolin [55759] (2 species)
   consists of six similar domains

7. Species Human (Homo sapiens) [TaxId:9606] [55761] (17 PDB entries)

8. Domain d1npha1: 1nph A:414-532 [85956]

Details for d1npha1

PDB Entry: 1nph, 3 Å

PDB Description: Gelsolin Domains 4-6 in Active, Actin Free Conformation Identifies Sites of Regulatory Calcium Ions

SCOP Domain Sequences for d1npha1:

Sequence, based on SEQRES records:

>d1npha1 d.109.1.1 (A:414-532) Gelsolin {Human (Homo sapiens)}
ddgtgqkqiwriegsnkvpvdpatygqfyggdsyiilynyrhggrqgqiiynwqgaqstq
devaasailtaqldeelggtpvqsrvvqgkepahlmslfggkpmiiykggtsrdggqta

Sequence, based on observed residues (ATOM records):

>d1npha1 d.109.1.1 (A:414-532) Gelsolin {Human (Homo sapiens)}
ddgtgqkqiwriegsnkvpvdpatygqfyggdsyiilynygqiiynwqgaqstqdevaas
ailtaqldeelggtpvqsrvvqgkepahlmslfggkpmiiykggtsrdggqta

Timeline for d1npha1:

• d1npha1 first appeared in SCOP 1.65
  
• d1npha1 appears in SCOP 1.69
  
• d1npha1 appears in the current release, SCOPe 2.08