SCOPe 2.06: Domain d1nn6a_: 1nn6 A:

Lineage for d1nn6a_ (1nn6 A:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Chymase (mast cell protease I) [89343] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89344] (11 PDB entries)

8. Domain d1nn6a_: 1nn6 A: [85893]
   proenzyme
   complexed with nag

Details for d1nn6a_

PDB Entry: 1nn6, 1.75 Å

PDB Description: human pro-chymase

PDB Compounds: (A:) Chymase

SCOPe Domain Sequences for d1nn6a_:

Sequence, based on SEQRES records:

>d1nn6a_ b.47.1.2 (A:) Chymase (mast cell protease I) {Human (Homo sapiens) [TaxId: 9606]}
ggteckphsrpymayleivtsngpskfcggflirrnfvltaahcagrsitvtlgahnite
eedtwqklevikqfrhpkyntstlhhdimllklkekasltlavgtlpfpsqfnfvppgrm
crvagwgrtgvlkpgsdtlqevklrlmdpqacshfrdfdhnlqlcvgnprktksafkgds
ggpllcagvaqgivsygrsdakppavftrishyrpwinqilqan

Sequence, based on observed residues (ATOM records):

>d1nn6a_ b.47.1.2 (A:) Chymase (mast cell protease I) {Human (Homo sapiens) [TaxId: 9606]}
ggteckphsrpymayleivtsngpskfcggflirrnfvltaahcagrsitvtlgahnite
eedtwqklevikqfrhpkyntstlhhdimllklkekasltlavgtlpfpsqfnfvppgrm
crvagwgrtgvlkpgsdtlqevklrlmdpqacshfrdfdhnlqlcvgnprktafkgdsgg
pllcagvaqgivsygrsdakppavftrishyrpwinqilqan

Timeline for d1nn6a_:

• d1nn6a_ first appeared in SCOP 1.65
  
• d1nn6a_ appears in SCOPe 2.05
  
• d1nn6a_ appears in SCOPe 2.07
  
• d1nn6a_ appears in the current release, SCOPe 2.08