SCOPe 2.05: Domain d1nn1a_: 1nn1 A:

Lineage for d1nn1a_ (1nn1 A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidylate kinase [52563] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [64010] (20 PDB entries)

8. Domain d1nn1a_: 1nn1 A: [85886]
   complexed with 2dt, anp, mg

Details for d1nn1a_

PDB Entry: 1nn1, 1.9 Å

PDB Description: crystal structure of human thymidylate kinase with ddtmp and appnhp

PDB Compounds: (A:) similar to THYMIDYLATE KINASE (DTMP KINASE)

SCOPe Domain Sequences for d1nn1a_:

Sequence; same for both SEQRES and ATOM records:

>d1nn1a_ c.37.1.1 (A:) Thymidylate kinase {Human (Homo sapiens) [TaxId: 9606]}
rrgalivlegvdragkstqsrklvealcaaghraellrfpersteigkllssylqkksdv
edhsvhllfsanrweqvplikeklsqgvtlvvdryafsgvaftgakenfsldwckqpdvg
lpkpdlvlflqlqladaakrgafgheryengafqeralrcfhqlmkdttlnwkmvdasks
ieavhedirvlsedaiatatekplgelwk

Timeline for d1nn1a_:

• d1nn1a_ first appeared in SCOP 1.65
  
• d1nn1a_ appears in SCOPe 2.04
  
• d1nn1a_ appears in SCOPe 2.06
  
• d1nn1a_ appears in the current release, SCOPe 2.08