SCOPe 2.01: Domain d1ni4b2: 1ni4 B:192-329

Lineage for d1ni4b2 (1ni4 B:192-329)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.48: TK C-terminal domain-like [52921] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 13245, strand 1 is antiparallel to the rest

4. Superfamily c.48.1: TK C-terminal domain-like [52922] (3 families)

5. Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain [52926] (4 proteins)

6. Protein E1-beta subunit of pyruvate dehydrogenase, C-domain [69521] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89713] (2 PDB entries)

8. Domain d1ni4b2: 1ni4 B:192-329 [85730]
   Other proteins in same PDB: d1ni4a_, d1ni4b1, d1ni4c_, d1ni4d1
   complexed with k, mg, tpp

Details for d1ni4b2

PDB Entry: 1ni4, 1.95 Å

PDB Description: human pyruvate dehydrogenase

PDB Compounds: (B:) Pyruvate dehydrogenase E1 component: Beta subunit

SCOPe Domain Sequences for d1ni4b2:

Sequence; same for both SEQRES and ATOM records:

>d1ni4b2 c.48.1.2 (B:192-329) E1-beta subunit of pyruvate dehydrogenase, C-domain {Human (Homo sapiens) [TaxId: 9606]}
lipigkakierqgthitvvshsrpvghcleaaavlskegvecevinmrtirpmdmetiea
svmktnhlvtveggwpqfgvgaeicarimegpafnfldapavrvtgadvpmpyakiledn
sipqvkdiifaikktlni

Timeline for d1ni4b2:

• d1ni4b2 first appeared in SCOP 1.65
  
• d1ni4b2 appears in SCOP 1.75
  
• d1ni4b2 appears in SCOPe 2.02
  
• d1ni4b2 appears in the current release, SCOPe 2.08