SCOPe 2.07: Domain d1n5lb_: 1n5l B:

Lineage for d1n5lb_ (1n5l B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidylate kinase [52563] (5 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [69482] (9 PDB entries)

8. Domain d1n5lb_: 1n5l B: [85335]
   complexed with act, dpo, mg, tmp, tyd

Details for d1n5lb_

PDB Entry: 1n5l, 2.3 Å

PDB Description: crystal structure of mycobacterium tuberculosis thymidylate kinase crystallized in sodium malonate, after catalysis in the crystal (2.3 a resolution)

PDB Compounds: (B:) thymidylate kinase

SCOPe Domain Sequences for d1n5lb_:

Sequence, based on SEQRES records:

>d1n5lb_ c.37.1.1 (B:) Thymidylate kinase {Mycobacterium tuberculosis [TaxId: 1773]}
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsaelagersrgraqrdpgrardnyerdaelqqrtgavya
elaaqgwggrwlvvgadvdpgrlaatla

Sequence, based on observed residues (ATOM records):

>d1n5lb_ c.37.1.1 (B:) Thymidylate kinase {Mycobacterium tuberculosis [TaxId: 1773]}
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsaelagersrgrarardnyerdaelqqrtgavyaelaaq
gwggrwlvvgadvdpgrlaatla

Timeline for d1n5lb_:

• d1n5lb_ first appeared in SCOP 1.65
  
• d1n5lb_ appears in SCOPe 2.06
  
• d1n5lb_ appears in the current release, SCOPe 2.08