SCOPe 2.08: Domain d1n5ka_: 1n5k A:

Lineage for d1n5ka_ (1n5k A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidylate kinase [52563] (5 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [69482] (9 PDB entries)

8. Domain d1n5ka_: 1n5k A: [85332]
   complexed with act, mg, tmp

Details for d1n5ka_

PDB Entry: 1n5k, 2.1 Å

PDB Description: crystal structure of mycobacterium tuberculosis thymidylate kinase crystallized in sodium malonate (resolution 2.1 a)

PDB Compounds: (A:) thymidylate kinase

SCOPe Domain Sequences for d1n5ka_:

Sequence, based on SEQRES records:

>d1n5ka_ c.37.1.1 (A:) Thymidylate kinase {Mycobacterium tuberculosis [TaxId: 1773]}
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsaelagersrgraqrdpgrardnyerdaelqqrtgavya
elaaqgwggrwlvvgadvdpgrlaatla

Sequence, based on observed residues (ATOM records):

>d1n5ka_ c.37.1.1 (A:) Thymidylate kinase {Mycobacterium tuberculosis [TaxId: 1773]}
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsaelagerrdnyerdaelqqrtgavyaelaaqgwggrwl
vvgadvdpgrlaatla

Timeline for d1n5ka_:

• d1n5ka_ first appeared in SCOP 1.65
  
• d1n5ka_ appears in SCOPe 2.07