Lineage for d1n4xl_ (1n4x L:)

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 781542Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 781543Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 781544Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (32 proteins)
  6. 782637Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 782864Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (127 PDB entries)
    Uniprot P01631 #KV2G_MOUSE Ig kappa chain V-II region 26-10; 79% sequence identity
    Uniprot P06310 # KV2F_HUMAN IG KAPPA CHAIN V-II REGION RPMI 6410 PRECURSOR
    Uniprot P03976 # KV2E_MOUSE (P03976) Ig kappa chain V-II region 17S29.1
    Uniprot P01642 21-115 #
    KV2G_MOUSE IG KAPPA CHAIN V-II REGION 26-10
    Uniprot P01631 #KV2G_MOUSE Ig kappa chain V-II region 26-10; 79% sequence identity ! Uniprot P06310 # KV2F_HUMAN IG KAPPA CHAIN V-II REGION RPMI 6410 PRECURSOR ! Uniprot P03976 # KV2E_MOUSE (P03976) Ig kappa chain V-II region 17S29.1 ! Uniprot P01642 21-115 # ! KV2G_MOUSE IG KAPPA CHAIN V-II REGION 26-10
  8. 782875Domain d1n4xl_: 1n4x L: [85326]
    Other proteins in same PDB: d1n4xh_, d1n4xi_
    part of scFv 1695

Details for d1n4xl_

PDB Entry: 1n4x (more details), 1.7 Å

PDB Description: structure of scfv 1696 at acidic ph
PDB Compounds: (L:) immunoglobulin kappa chain variable region

SCOP Domain Sequences for d1n4xl_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1n4xl_ b.1.1.1 (L:) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1 [TaxId: 10090]}
mdilmtqtplylpvslgdqasiscrssqtivhnngntylewylqkpgqspqlliykvsnr
fsgvpdrfsgsgsgtdftlkisrveaedlgiyycfqgshfpptfgggtkleia

SCOP Domain Coordinates for d1n4xl_:

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Timeline for d1n4xl_: