SCOP 1.65: Domain d1muoa_: 1muo A:

Lineage for d1muoa_ (1muo A:)

1. Root: SCOP 1.65

2. Class d: Alpha and beta proteins (a+b) [53931] (234 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (41 proteins)
   members organised in the groups and subfamiles specified by the comments

6. Protein Aurora-related kinase 1 (aurora-2) [90038] (1 species)
   OPK group; AIRK subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [90039] (1 PDB entry)

8. Domain d1muoa_: 1muo A: [85110]
   complexed with adn

Details for d1muoa_

PDB Entry: 1muo, 2.9 Å

PDB Description: crystal structure of aurora-2, an oncogenic serine-threonine kinase

SCOP Domain Sequences for d1muoa_:

Sequence, based on SEQRES records:

>d1muoa_ d.144.1.7 (A:) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens)}
waledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqsh
lrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsyc
hskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlcgtldylppemiegrmhd
ekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhn
psqrpmlrevlehpwitanss

Sequence, based on observed residues (ATOM records):

>d1muoa_ d.144.1.7 (A:) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens)}
waledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqsh
lrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsyc
hskrvihrdikpenlllgsagelkiadfgwslcgtldylppemiegrmhdekvdlwslgv
lcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqrpmlrev
lehpwitanss

Timeline for d1muoa_:

• d1muoa_ is new in SCOP 1.65
  
• d1muoa_ appears in SCOP 1.67
  
• d1muoa_ appears in the current release, SCOPe 2.08