SCOP 1.67: Domain d1ms8b2: 1ms8 B:2-399

Lineage for d1ms8b2 (1ms8 B:2-399)

1. Root: SCOP 1.67

2. Class b: All beta proteins [48724] (141 folds)

3. Fold b.68: 6-bladed beta-propeller [50938] (10 superfamilies)
   consists of six 4-stranded beta-sheet motifs; meander

4. Superfamily b.68.1: Sialidases (neuraminidases) [50939] (1 family)

5. Family b.68.1.1: Sialidases (neuraminidases) [50940] (8 proteins)

6. Protein Trypanosoma sialidase [82164] (2 species)

7. Species Parasitic flagellate protozoan (Trypanosoma cruzi) [TaxId:5693] [89371] (8 PDB entries)

8. Domain d1ms8b2: 1ms8 B:2-399 [85087]
   Other proteins in same PDB: d1ms8a1, d1ms8b1
   complexed with dan; mutant

Details for d1ms8b2

PDB Entry: 1ms8, 2 Å

PDB Description: triclinic form of trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-n-acetylneuraminic acid (dana)

SCOP Domain Sequences for d1ms8b2:

Sequence; same for both SEQRES and ATOM records:

>d1ms8b2 b.68.1.1 (B:2-399) Trypanosoma sialidase {Parasitic flagellate protozoan (Trypanosoma cruzi)}
apgssrvelfkrqsskvpfekdgkvtervvhsfrlpalvnvdgvmvaiadaryetsfdns
lidtvakysvddgetwetqiaiknsrassvsrvvdptvivkgnklyvlvgsynssrsywt
shgdardwdillavgevtkstaggkitasikwgspvslkeffpaemegmhtnqflggagv
aivasngnlvypvqvtnkkkqvfskifysedegktwkfgkgrsafgcsepvalewegkli
intrvdyrrrlvyessdmgntwleavgtlsrvwgpspksnqpgsqssftavtiegmrvml
fthplnfkgrwlrdrlnlwltdnqriynvgqvsigdensayssvlykddklyclheinsn
evyslvfarlvgelriiksvlqswknwdshlssictpa

Timeline for d1ms8b2:

• d1ms8b2 first appeared in SCOP 1.65
  
• d1ms8b2 appears in SCOP 1.69
  
• d1ms8b2 appears in the current release, SCOPe 2.08