SCOP 1.71: Domain d1ms1b2: 1ms1 B:1-399

Lineage for d1ms1b2 (1ms1 B:1-399)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.68: 6-bladed beta-propeller [50938] (11 superfamilies)
   consists of six 4-stranded beta-sheet motifs; meander

4. Superfamily b.68.1: Sialidases [50939] (2 families)

5. Family b.68.1.1: Sialidases (neuraminidases) [50940] (9 proteins)

6. Protein Trypanosoma sialidase [82164] (2 species)

7. Species Parasitic flagellate protozoan (Trypanosoma cruzi) [TaxId:5693] [89371] (11 PDB entries)

8. Domain d1ms1b2: 1ms1 B:1-399 [85067]
   Other proteins in same PDB: d1ms1a1, d1ms1b1
   complexed with dan, gol; mutant

Details for d1ms1b2

PDB Entry: 1ms1, 1.8 Å

PDB Description: monoclinic form of trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-n-acetylneuraminic acid (dana)

SCOP Domain Sequences for d1ms1b2:

Sequence; same for both SEQRES and ATOM records:

>d1ms1b2 b.68.1.1 (B:1-399) Trypanosoma sialidase {Parasitic flagellate protozoan (Trypanosoma cruzi)}
lapgssrvelfkrqsskvpfekdgkvtervvhsfrlpalvnvdgvmvaiadaryetsfdn
slidtvakysvddgetwetqiaiknsrassvsrvvdptvivkgnklyvlvgsynssrsyw
tshgdardwdillavgevtkstaggkitasikwgspvslkeffpaemegmhtnqflggag
vaivasngnlvypvqvtnkkkqvfskifysedegktwkfgkgrsafgcsepvalewegkl
iintrvdyrrrlvyessdmgntwleavgtlsrvwgpspksnqpgsqssftavtiegmrvm
lfthplnfkgrwlrdrlnlwltdnqriynvgqvsigdensayssvlykddklyclheins
nevyslvfarlvgelriiksvlqswknwdshlssictpa

Timeline for d1ms1b2:

• d1ms1b2 first appeared in SCOP 1.65
  
• d1ms1b2 appears in SCOP 1.69
  
• d1ms1b2 appears in SCOP 1.73
  
• d1ms1b2 appears in the current release, SCOPe 2.08