SCOPe 2.08: Domain d1m2za_: 1m2z A:

Lineage for d1m2za_ (1m2z A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Glucocorticoid receptor [89140] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89141] (8 PDB entries)

8. Domain d1m2za_: 1m2z A: [84768]
   complexed with coactivator peptide, chains B and E
   complexed with bog, dex

Details for d1m2za_

PDB Entry: 1m2z, 2.5 Å

PDB Description: crystal structure of a dimer complex of the human glucocorticoid receptor ligand-binding domain bound to dexamethasone and a tif2 coactivator motif

PDB Compounds: (A:) Glucocorticoid receptor

SCOPe Domain Sequences for d1m2za_:

Sequence; same for both SEQRES and ATOM records:

>d1m2za_ a.123.1.1 (A:) Glucocorticoid receptor {Human (Homo sapiens) [TaxId: 9606]}
atlpqltptlvslleviepevlyagydssvpdstwrimttlnmlggrqviaavkwakaip
gfrnlhlddqmtllqyswmslmafalgwrsyrqssanllcfapdliineqrmtlpcmydq
ckhmlyvsselhrlqvsyeeylcmktllllssvpkdglksqelfdeirmtyikelgkaiv
kregnssqnwqrfyqltklldsmhevvenllnycfqtfldktmsiefpemlaeiitnqip
kysngnikkllfhqk

Timeline for d1m2za_:

• d1m2za_ first appeared in SCOP 1.65
  
• d1m2za_ appears in SCOPe 2.07