SCOPe 2.03: Domain d1m2nb_: 1m2n B:

Lineage for d1m2nb_ (1m2n B:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like

4. Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families)
   binds cofactor molecules in the opposite direction than classical Rossmann fold

5. Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins)
   silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain

6. Protein AF1676, Sir2 homolog (Sir2-AF1?) [63985] (1 species)

7. Species Archaeoglobus fulgidus [TaxId:2234] [63986] (6 PDB entries)

8. Domain d1m2nb_: 1m2n B: [84757]
   complexed with oad, zn; mutant

Details for d1m2nb_

PDB Entry: 1m2n, 2.6 Å

PDB Description: sir2 homologues (d102g/f159a/r170a) mutant-2'-o-acetyl adp ribose complex

PDB Compounds: (B:) Silent Information Regulator 2

SCOPe Domain Sequences for d1m2nb_:

Sequence; same for both SEQRES and ATOM records:

>d1m2nb_ c.31.1.5 (B:) AF1676, Sir2 homolog (Sir2-AF1?) {Archaeoglobus fulgidus [TaxId: 2234]}
mdekllktiaeskylvaltgagvsaesgiptfrgkdglwnryrpeelanpqafakdpekv
wkwyawrmekvfnaqpnkahqafaelerlgvlkclitqnvdglheragsrnvihlhgslr
vvrctscnnsfevesapkipplpkcdkcgsllrpgvvwagemlppdvldaamreveradv
iivagtsavvqpaaslplivkqrggaiieinpdetpltpiadyslrgkagevmdelvrhv
rkalslkln

Timeline for d1m2nb_:

• d1m2nb_ first appeared in SCOP 1.65
  
• d1m2nb_ appears in SCOPe 2.02
  
• d1m2nb_ appears in SCOPe 2.04
  
• d1m2nb_ appears in the current release, SCOPe 2.08, called d1m2nb1