SCOPe 2.08: Domain d1lrta1: 1lrt A:2-100,A:231-485

Lineage for d1lrta1 (1lrt A:2-100,A:231-485)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families)
   The phosphate moiety of substrate binds in the 'common' phosphate-binding site

5. Family c.1.5.1: Inosine monophosphate dehydrogenase (IMPDH) [51413] (1 protein)

6. Protein Inosine monophosphate dehydrogenase (IMPDH) [51414] (8 species)

7. Species Tritrichomonas foetus [TaxId:5724] [51417] (10 PDB entries)

8. Domain d1lrta1: 1lrt A:2-100,A:231-485 [84685]
   there are two CBS domains in the disordered region 101-230
   complexed with bog, imp, k, tad, trs

Details for d1lrta1

PDB Entry: 1lrt, 2.2 Å

PDB Description: crystal structure of ternary complex of tritrichomonas foetus inosine- 5'-monophosphate dehydrogenase: structural characterization of nad+ site in microbial enzyme

PDB Compounds: (A:) inosine-5'-monophosphate dehydrogenase

SCOPe Domain Sequences for d1lrta1:

Sequence, based on SEQRES records:

>d1lrta1 c.1.5.1 (A:2-100,A:231-485) Inosine monophosphate dehydrogenase (IMPDH) {Tritrichomonas foetus [TaxId: 5724]}
akyynepchtfneyllipglstvdcipsnvnlstplvkfqkgqqseinlkiplvsaimqs
vsgekmaialareggisfifgsqsiesqaamvhavknfkXrylvgagintrdfrervpal
veagadvlcidssdgfsewqkitigwirdkygdkvkvgagnivdgegfryladagadfik
igigggsicitreqkgigrgqatavidvvaernkyfeetgiyipvcsdggivydyhmtla
lamgadfimlgryfarfeesptrkvtingsvmkeywgegssrarnwqrydlggkqklsfe
egvdsyvpyagklkdnveaslnkvkstmcncgaltipqlqskakitlvssvsive

Sequence, based on observed residues (ATOM records):

>d1lrta1 c.1.5.1 (A:2-100,A:231-485) Inosine monophosphate dehydrogenase (IMPDH) {Tritrichomonas foetus [TaxId: 5724]}
akyynepchtfneyllipglstvdcipsnvnlstplvkfqkgqqseinlkiplvsaimqs
vsgekmaialareggisfifgsqsiesqaamvhavknfkXrylvgagintrdfrervpal
veagadvlcidssdgfsewqkitigwirdkygdkvkvgagnivdgegfryladagadfik
igigggsiceqkgigrgqatavidvvaernkyfeetgiyipvcsdggivydyhmtlalam
gadfimlgryfarfeesptrkvtingsvmkeywgegssrarnweegvdsyvpyagklkdn
veaslnkvkstmcncgaltipqlqskakitlvssvsive

Timeline for d1lrta1:

• d1lrta1 first appeared in SCOP 1.65
  
• d1lrta1 appears in SCOPe 2.07