Lineage for d1lhzb1 (1lhz B:1-112)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2344608Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2344609Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2344610Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 2346703Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 2346735Species Human (Homo sapiens), cluster 4 [TaxId:9606] [88539] (23 PDB entries)
  8. 2346739Domain d1lhzb1: 1lhz B:1-112 [84614]
    Other proteins in same PDB: d1lhza2, d1lhzb2
    part of amyloidogenic protein BUR

Details for d1lhzb1

PDB Entry: 1lhz (more details), 2.3 Å

PDB Description: Structure of a Human Bence-Jones Dimer Crystallized in U.S. Space Shuttle Mission STS-95: 293K
PDB Compounds: (B:) immunoglobulin lambda light chain

SCOPe Domain Sequences for d1lhzb1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1lhzb1 b.1.1.1 (B:1-112) Immunoglobulin light chain lambda variable domain, VL-lambda {Human (Homo sapiens), cluster 4 [TaxId: 9606]}

SCOPe Domain Coordinates for d1lhzb1:

Click to download the PDB-style file with coordinates for d1lhzb1.
(The format of our PDB-style files is described here.)

Timeline for d1lhzb1:

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