SCOPe 2.05: Domain d1l9ka_: 1l9k A:

Lineage for d1l9ka_ (1l9k A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (58 families)

5. Family c.66.1.25: mRNA cap methylase [88785] (3 proteins)

6. Protein An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 [89741] (2 species)
   structurally and functionally similar to VP39

7. Species Flavivirus (Dengue virus type 2) [TaxId:12637] [89742] (8 PDB entries)
   Uniprot P12823 2495-2756

8. Domain d1l9ka_: 1l9k A: [84569]
   complexed with sah, so4

Details for d1l9ka_

PDB Entry: 1l9k, 2.4 Å

PDB Description: dengue methyltransferase

PDB Compounds: (A:) RNA-directed RNA polymerase

SCOPe Domain Sequences for d1l9ka_:

Sequence; same for both SEQRES and ATOM records:

>d1l9ka_ c.66.1.25 (A:) An RNA cap (nucleoside-2'-O-)-methyltransferase domain of RNA polymerase NS5 {Flavivirus (Dengue virus type 2) [TaxId: 12637]}
etlgekwksrlnalgksefqiykksgiqevdrtlakegikrgetdhhavsrgsaklrwfv
ernlvtpegkvvdlgcgrggwsyycgglknvrevkgltkggpgheepipmstygwnlvrl
qsgvdvffippercdtllcdigesspnptveagrtlrvlnlvenwlsnntqfcvkvlnpy
mssviekmealqrkhggalvrnplsrnsthemywvsnasgnivssvnmisrmlinrftmr
hkkatyepdvdlgsgtrnigi

Timeline for d1l9ka_:

• d1l9ka_ first appeared in SCOP 1.65
  
• d1l9ka_ appears in SCOPe 2.04
  
• d1l9ka_ appears in SCOPe 2.06
  
• d1l9ka_ appears in the current release, SCOPe 2.08