SCOP 1.75: Domain d1l8na1: 1l8n A:143-678

Lineage for d1l8na1 (1l8n A:143-678)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (14 families)

5. Family c.1.8.10: alpha-D-glucuronidase/Hyaluronidase catalytic domain [82253] (3 proteins)
   Glycosyl hydrolase family 67, GH67; structurally related to GH20; contains extra C-terminal alpha-helical subdomain

6. Protein alpha-D-glucuronidase catalytic domain [82254] (2 species)
   inverting reaction mechanism

7. Species Bacillus stearothermophilus [TaxId:1422] [82256] (7 PDB entries)

8. Domain d1l8na1: 1l8n A:143-678 [84564]
   Other proteins in same PDB: d1l8na2
   complexed with gcw, gol, xyp

Details for d1l8na1

PDB Entry: 1l8n, 1.5 Å

PDB Description: the 1.5a crystal structure of alpha-d-glucuronidase from bacillus stearothermophilus t-1, complexed with 4-o-methyl-glucuronic acid and xylotriose

PDB Compounds: (A:) alpha-d-glucuronidase

SCOP Domain Sequences for d1l8na1:

Sequence, based on SEQRES records:

>d1l8na1 c.1.8.10 (A:143-678) alpha-D-glucuronidase catalytic domain {Bacillus stearothermophilus [TaxId: 1422]}
rlrminhwdnmdgsiergyagrsiffvddqfvkqnqrikdyarllasvginaisinnvnv
hktetklitdhflpdvaevadifrtygiktflsinyaspieigglptadpldpevrwwwk
etakriyqyipdfggfvvkadsefrpgpftygrdhaeganmlaealapfgglviwrcfvy
ncqqdwrdrttdrakaaydhfkpldgqfrenvilqikngpmdfqvrepvsplfgampktn
qmmevqitqeytgqqkhlcflipqwkevldfdtyakgkgsevkkvidgslfdyrysgiag
vsnigsdpnwtghtlaqanlygfgrlawnpdlsaeeianewvvqtfgddsqvvetiswml
lsswriyenytsplgvgwmvnpghhygpnvdgyeyshwgtyhyadrdgigvdrtvatgtg
ytaqyfpenaamyesldtcpdelllffhhvpythrlhsgetviqhiynthfegveqakql
rkrweqlkgkidekryhdvlerltiqvehakewrdvintyfyrksgiddqygrkiy

Sequence, based on observed residues (ATOM records):

>d1l8na1 c.1.8.10 (A:143-678) alpha-D-glucuronidase catalytic domain {Bacillus stearothermophilus [TaxId: 1422]}
rlrminhwdnmdgsiergyagrsiffvddqfvnqrikdyarllasvginaisinnvnvhk
tetklitdhflpdvaevadifrtygiktflsinyaspieigglptadpldpevrwwwket
akriyqyipdfggfvvkadsefrpgpftygrdhaeganmlaealapfgglviwrcfvync
qqdwrdrttdrakaaydhfkpldgqfrenvilqikngpmdfqvrepvsplfgampktnqm
mevqitqeytgqqkhlcflipqwkevldfdtyakgkgsevkkvidgslfdyrysgiagvs
nigsdpnwtghtlaqanlygfgrlawnpdlsaeeianewvvqtfgddsqvvetiswmlls
swriyenytsplgvgwmvnpghhygpnvdgyeyshwgtyhyadrdgigvdrtvatgtgyt
aqyfpenaamyesldtcpdelllffhhvpythrlhsgetviqhiynthfegveqakqlrk
rweqlkgkidekryhdvlerltiqvehakewrdvintyfyrksgiddqygrkiy

Timeline for d1l8na1:

• d1l8na1 first appeared in SCOP 1.65
  
• d1l8na1 appears in SCOP 1.73
  
• d1l8na1 appears in SCOPe 2.01
  
• d1l8na1 appears in the current release, SCOPe 2.08