SCOPe 2.05: Domain d1kmqa_: 1kmq A:

Lineage for d1kmqa_ (1kmq A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein RhoA [52612] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52613] (23 PDB entries)
   Uniprot P61586 2-181

8. Domain d1kmqa_: 1kmq A: [84412]
   complexed with dio, gnp, mg; mutant

Details for d1kmqa_

PDB Entry: 1kmq, 1.55 Å

PDB Description: crystal structure of a constitutively activated rhoa mutant (q63l)

PDB Compounds: (A:) transforming protein rhoa

SCOPe Domain Sequences for d1kmqa_:

Sequence; same for both SEQRES and ATOM records:

>d1kmqa_ c.37.1.8 (A:) RhoA {Human (Homo sapiens) [TaxId: 9606]}
irkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtagl
edydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlrn
dehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq

Timeline for d1kmqa_:

• d1kmqa_ first appeared in SCOP 1.65
  
• d1kmqa_ appears in SCOPe 2.04
  
• d1kmqa_ appears in SCOPe 2.06
  
• d1kmqa_ appears in the current release, SCOPe 2.08