Lineage for d1jcnb3 (1jcn B:181-231)

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 721299Fold d.37: CBS-domain [54630] (1 superfamily)
    core: beta-alpha-beta(4); 2 layers: alpha/beta
  4. 721300Superfamily d.37.1: CBS-domain [54631] (1 family) (S)
  5. 721301Family d.37.1.1: CBS-domain [54632] (10 proteins)
    Pfam PF00571; pairs of CBS domains dimerize to form a stable globular domain
  6. 721353Protein Type II inosine monophosphate dehydrogenase CBS domains [54633] (4 species)
    contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals
  7. 721357Species Human (Homo sapiens), type I [TaxId:9606] [89899] (1 PDB entry)
  8. 721361Domain d1jcnb3: 1jcn B:181-231 [84165]
    Other proteins in same PDB: d1jcna1, d1jcnb1
    both CBS domains are partly disordered in both chains, A and B
    complexed with cpr

Details for d1jcnb3

PDB Entry: 1jcn (more details), 2.5 Å

PDB Description: binary complex of human type-i inosine monophosphate dehydrogenase with 6-cl-imp
PDB Compounds: (B:) inosine monophosphate dehydrogenase I

SCOP Domain Sequences for d1jcnb3:

Sequence, based on SEQRES records: (download)

>d1jcnb3 d.37.1.1 (B:181-231) Type II inosine monophosphate dehydrogenase CBS domains {Human (Homo sapiens), type I [TaxId: 9606]}
prielvvapagvtlkeaneilqrskkgklpivndcdelvaiiartdlkknr

Sequence, based on observed residues (ATOM records): (download)

>d1jcnb3 d.37.1.1 (B:181-231) Type II inosine monophosphate dehydrogenase CBS domains {Human (Homo sapiens), type I [TaxId: 9606]}
prielvvapagvtlkeaneilqrskkgklpivndcdelvrtdlkknr

SCOP Domain Coordinates for d1jcnb3:

Click to download the PDB-style file with coordinates for d1jcnb3.
(The format of our PDB-style files is described here.)

Timeline for d1jcnb3: