SCOP 1.67: Domain d1jcnb3: 1jcn B:181-231

Lineage for d1jcnb3 (1jcn B:181-231)

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.37: CBS-domain [54630] (1 superfamily)
   core: beta-alpha-beta(4); 2 layers: alpha/beta

4. Superfamily d.37.1: CBS-domain [54631] (1 family)

5. Family d.37.1.1: CBS-domain [54632] (4 proteins)
   pairs of CBS domains dimerize to form a stable globular domain

6. Protein Type II inosine monophosphate dehydrogenase CBS domains [54633] (4 species)
   contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals

7. Species Human (Homo sapiens), type I [TaxId:9606] [89899] (1 PDB entry)

8. Domain d1jcnb3: 1jcn B:181-231 [84165]
   Other proteins in same PDB: d1jcna1, d1jcnb1
   both CBS domains are partly disordered in both chains, A and B
   complexed with cpr

Details for d1jcnb3

PDB Entry: 1jcn, 2.5 Å

PDB Description: binary complex of human type-i inosine monophosphate dehydrogenase with 6-cl-imp

SCOP Domain Sequences for d1jcnb3:

Sequence, based on SEQRES records:

>d1jcnb3 d.37.1.1 (B:181-231) Type II inosine monophosphate dehydrogenase CBS domains {Human (Homo sapiens), type I}
prielvvapagvtlkeaneilqrskkgklpivndcdelvaiiartdlkknr

Sequence, based on observed residues (ATOM records):

>d1jcnb3 d.37.1.1 (B:181-231) Type II inosine monophosphate dehydrogenase CBS domains {Human (Homo sapiens), type I}
prielvvapagvtlkeaneilqrskkgklpivndcdelvrtdlkknr

Timeline for d1jcnb3:

• d1jcnb3 first appeared in SCOP 1.65
  
• d1jcnb3 appears in SCOP 1.69
  
• d1jcnb3 last appears in SCOP 1.73