SCOP 1.67: Domain d1j1ed_: 1j1e D:

Lineage for d1j1ed_ (1j1e D:)

1. Root: SCOP 1.67

2. Class a: All alpha proteins [46456] (202 folds)

3. Fold a.39: EF Hand-like [47472] (4 superfamilies)
   core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.39.1: EF-hand [47473] (10 families)
   Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

5. Family a.39.1.5: Calmodulin-like [47502] (21 proteins)
   Duplication: made with two pairs of EF-hands

6. Protein Troponin C [47503] (5 species)

7. Species Human (Homo sapiens), cardiac isoform [TaxId:9606] [47508] (8 PDB entries)

8. Domain d1j1ed_: 1j1e D: [83972]
   Other proteins in same PDB: d1j1eb_, d1j1ec_, d1j1ee_, d1j1ef_
   complexed with ca; mutant

Details for d1j1ed_

PDB Entry: 1j1e, 3.3 Å

PDB Description: crystal structure of the 52kda domain of human cardiac troponin in the ca2+ saturated form

SCOP Domain Sequences for d1j1ed_:

Sequence, based on SEQRES records:

>d1j1ed_ a.39.1.5 (D:) Troponin C {Human (Homo sapiens), cardiac isoform}
mddiykaaveqlteeqknefkaafdifvlgaedgsistkelgkvmrmlgqnptpeelqem
idevdedgsgtvdfdeflvmmvrsmkddskgkseeelsdlfrmfdknadgyidleelkim
lqatgetiteddieelmkdgdknndgridydeflefmkgve

Sequence, based on observed residues (ATOM records):

>d1j1ed_ a.39.1.5 (D:) Troponin C {Human (Homo sapiens), cardiac isoform}
mddiykaaveqlteeqknefkaafdifvlgaedgsistkelgkvmrmlnptpeelqemid
evdedgsgtvdfdeflvmmvrsmkddskgkseeelsdlfrmfdknadgyidleelkimlq
atgetiteddieelmkdgdknndgridydeflefmkgve

Timeline for d1j1ed_:

• d1j1ed_ first appeared in SCOP 1.65
  
• d1j1ed_ appears in SCOP 1.69
  
• d1j1ed_ appears in the current release, SCOPe 2.08