SCOP 1.65: Domain d1hxca2: 1hxc A:221-548

Lineage for d1hxca2 (1hxc A:221-548)

1. Root: SCOP 1.65

2. Class a: All alpha proteins [46456] (179 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (5 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.3: Terpenoid cyclase C-terminal domain [48583] (2 proteins)

6. Protein 5-Epi-aristolochene synthase [48584] (1 species)

7. Species Tobacco (Nicotiana tabacum) [TaxId:4097] [48585] (7 PDB entries)

8. Domain d1hxca2: 1hxc A:221-548 [83644]
   Other proteins in same PDB: d1hxca1
   complexed with fhp; mutant

Details for d1hxca2

PDB Entry: 1hxc, 2.25 Å

PDB Description: crystal structure of teas c440w

SCOP Domain Sequences for d1hxca2:

Sequence, based on SEQRES records:

>d1hxca2 a.128.1.3 (A:221-548) 5-Epi-aristolochene synthase {Tobacco (Nicotiana tabacum)}
knnvllrfakldfnllqmlhkqelaqvsrwwkdldfvttlpyardrvvecyfwalgvyfe
pqysqarvmlvktismisivddtfdaygtvkeleaytdaiqrwdineidrlpdymkisyk
aildlykdyekelssagrshivchaiermkevvrnynvestwfiegytppvseylsnala
tttyyylattsylgmksateqdfewlsknpkileasviiwrviddtatyeveksrgqiat
gieccmrdygistkeamakfqnmaetawkdinegllrptpvstefltpilnlarivevty
ihnldgythpeevlkphiinllvdsiki

Sequence, based on observed residues (ATOM records):

>d1hxca2 a.128.1.3 (A:221-548) 5-Epi-aristolochene synthase {Tobacco (Nicotiana tabacum)}
knnvllrfakldfnllqmlhkqelaqvsrwwkdldfvttlpyardrvvecyfwalgvyfe
pqysqarvmlvktismisivddtfdaygtvkeleaytdaiqrwdineidrlpdymkisyk
aildlykdyekelssagrshivchaiermkevvrnynvestwfiegytppvseylsnala
tttyyylattsylgmksateqdfewlsknpkileasviiwrviddtatyeveksrgqiat
gieccmrdygistkeamakfqnmaetawkdinegllrptpvstefltpilnlarivevty
vlkphiinllvdsiki

Timeline for d1hxca2:

• d1hxca2 is new in SCOP 1.65
  
• d1hxca2 appears in SCOP 1.67
  
• d1hxca2 appears in the current release, SCOPe 2.08