SCOP 1.71: Domain d1gzoa_: 1gzo A:

Lineage for d1gzoa_ (1gzo A:)

1. Root: SCOP 1.71

2. Class d: Alpha and beta proteins (a+b) [53931] (286 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (60 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Pkb kinase (Akt-2) [82791] (1 species)
   AGC group; RAC/Akt subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [82792] (7 PDB entries)

8. Domain d1gzoa_: 1gzo A: [83408]

Details for d1gzoa_

PDB Entry: 1gzo, 2.75 Å

PDB Description: structure of protein kinase b unphosphorylated

SCOP Domain Sequences for d1gzoa_:

Sequence, based on SEQRES records:

>d1gzoa_ d.144.1.7 (A:) Pkb kinase (Akt-2) {Human (Homo sapiens)}
kvtmndfdylkllgkgtfgkvilvrekatgryyamkilrkeviiakdevahtvtesrvlq
ntrhpfltalkyafqthdrlcfvmeyanggelffhlsrervfteerarfygaeivsaley
lhsrdvvyrdiklenlmldkdghikitdfglckegisdgatmktfcgtpeylapevledn
dygravdwwglgvvmyemmcgrlpfynqdherlfelilmeeirfprtlspeaksllagll
kkdpkqrlgggpsdakevmehrfflsinwqdvvqkkllppfkpqvtsevdtryfdde

Sequence, based on observed residues (ATOM records):

>d1gzoa_ d.144.1.7 (A:) Pkb kinase (Akt-2) {Human (Homo sapiens)}
kvtmndfdylkllgkgtfgkvilvrekatgryyamkilrkevivtesrvlqntrhpflta
lkyafqthdrlcfvmeyanggelffhlsrervfteerarfygaeivsaleylhsrdvvyr
diklenlmldkdghikitdfgltpeylapevledndygravdwwglgvvmyemmcgrlpf
ynqdherlfelilmeeirfprtlspeaksllagllkkdpkqrlgggpsdakevmehrffl
sinwqdvvqkkllppfkpqvtsevdtryfdde

Timeline for d1gzoa_:

• d1gzoa_ first appeared in SCOP 1.65
  
• d1gzoa_ appears in SCOP 1.69
  
• d1gzoa_ appears in SCOP 1.73
  
• d1gzoa_ appears in the current release, SCOPe 2.08