Lineage for d2hwd.1 (2hwd 4:,2:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2075417Fold b.121: Nucleoplasmin-like/VP (viral coat and capsid proteins) [88632] (7 superfamilies)
    sandwich; 8 strands in 2 sheets; jelly-roll; some members can have additional 1-2 strands
    characteristic interaction between the domains of this fold allows the formation of five-fold and pseudo six-fold assemblies
  4. 2075626Superfamily b.121.4: Positive stranded ssRNA viruses [88633] (10 families) (S)
  5. 2075627Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4) [88634] (10 protein domains)
    the order of the chains N-VP0-VP3-VP1-C is as in the polyprotein; VP0 is cleaved later upon capsid assembly to VP4 and VP2
    there is a different order in the shuffled genome of insect picorna-like proteins (Cricket paralysis virus)
  6. 2075745Protein Rhinovirus coat proteins [49670] (5 species)
  7. 2075778Species Human rhinovirus A 1A (HRV-1A) [TaxId:12134] [49673] (4 PDB entries)
  8. 2075788Domain d2hwd.1: 2hwd 4:,2: [83133]
    complexed with w91

Details for d2hwd.1

PDB Entry: 2hwd (more details), 3.8 Å

PDB Description: a comparison of the anti-rhinoviral drug binding pocket in hrv14 and hrv1a
PDB Compounds: (2:) human rhinovirus 1a coat protein (subunit vp2), (4:) human rhinovirus 1a coat protein (subunit vp4)

SCOPe Domain Sequences for d2hwd.1:

Sequence; same for both SEQRES and ATOM records: (download)

>g2hwd.1 b.121.4.1 (4:,2:) Rhinovirus coat proteins {Human rhinovirus A 1A (HRV-1A) [TaxId: 12134]}

SCOPe Domain Coordinates for d2hwd.1:

Click to download the PDB-style file with coordinates for d2hwd.1.
(The format of our PDB-style files is described here.)

Timeline for d2hwd.1: