Class d: Alpha and beta proteins (a+b) [53931] (376 folds) |
Fold d.92: Zincin-like [55485] (2 superfamilies) contains mixed beta sheet with connection over free side of the sheet |
Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families) |
Family d.92.1.5: Neurolysin-like [55505] (5 proteins) combines M2, M3 and M32 families of metalloproteases the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain |
Protein Angiotensin converting enzyme, ACE [82733] (2 species) M2 family member; overall fold is similar to that of neurolysin but is less elaborated |
Species Human (Homo sapiens) [TaxId:9606] [82734] (9 PDB entries) Uniprot P22966 |
Domain d1o86a_: 1o86 A: [81177] complexed with cl, gly, lpr, zn |
Domain d1o8aa_: 1o8a A: [81179] complexed with act, cl, nag, ndg, nxa, zn |
Domain d1uzea_: 1uze A: [108174] complexed with cl, eal, gly, zn |
Domain d1uzfa_: 1uzf A: [108175] complexed with cl, mco, nag, zn |
Domain d2oc2a_: 2oc2 A: [139007] automated match to d1o86a_ complexed with cl, rx3, zn |
Domain d2xy9a_: 2xy9 A: [170474] automated match to d1o86a_ complexed with 3es, act, cl, epe, nag, zn |
Domain d3bkka_: 3bkk A: [172679] automated match to d1o86a_ complexed with cl, kaf, nag, zn |
Domain d3bkla_: 3bkl A: [172680] automated match to d1o86a_ complexed with act, cl, gol, kaw, nag, zn |
Domain d3l3na_: 3l3n A: [179912] automated match to d1o86a_ complexed with cl, lsw, zn |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.92.1.5 Angiotensin converting enzyme, ACE: