Lineage for Protein: Angiotensin converting enzyme, ACE

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1423492Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. 1423493Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families) (S)
  5. 1423668Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
    combines M2, M3 and M32 families of metalloproteases
    the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain
  6. 1423682Protein Angiotensin converting enzyme, ACE [82733] (2 species)
    M2 family member; overall fold is similar to that of neurolysin but is less elaborated


  1. 1423683Fruit fly (Drosophila melanogaster) [TaxId:7227] [89991] (3 PDB entries)
    1. Domains for 1j36:
      1. 1423684Domain d1j36a_: 1j36 A: [84054]
        complexed with lpr, zn
      2. 1423685Domain d1j36b_: 1j36 B: [84055]
        complexed with lpr, zn
    2. Domains for 1j37:
      1. 1423686Domain d1j37a_: 1j37 A: [84056]
        complexed with x8z, zn
      2. 1423687Domain d1j37b_: 1j37 B: [84057]
        complexed with x8z, zn
    3. Domains for 1j38:
      1. 1423688Domain d1j38a_: 1j38 A: [84058]
        complexed with zn
      2. 1423689Domain d1j38b_: 1j38 B: [84059]
        complexed with zn
  2. 1423690Human (Homo sapiens) [TaxId:9606] [82734] (11 PDB entries)
    Uniprot P22966
    1. Domain for 1o86:
    2. Domain for 1o8a:
    3. Domain for 1uze:
    4. Domain for 1uzf:
    5. Domain for 2oc2:
    6. Domain for 2xy9:
    7. Domain for 3bkk:
    8. Domain for 3bkl:
    9. Domain for 3l3n:
    10. Domain for 4bzr:
    11. Domain for 4ca5:

More info for Protein Angiotensin converting enzyme, ACE from d.92.1.5: Neurolysin-like

Timeline for Protein Angiotensin converting enzyme, ACE from d.92.1.5: Neurolysin-like: