Lineage for Protein: Angiotensin converting enzyme, ACE

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families) (S)
  5. Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
    combines M2, M3 and M32 families of metalloproteases
    the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain
  6. Protein Angiotensin converting enzyme, ACE [82733] (2 species)
    M2 family member; overall fold is similar to that of neurolysin but is less elaborated

Species:

  1. Fruit fly (Drosophila melanogaster) [TaxId:7227] [89991] (3 PDB entries)
    1. Domains for 1j36:
      1. Domain d1j36a1: 1j36 A:23-615 [84054]
        Other proteins in same PDB: d1j36a2, d1j36b2
        complexed with lpr, zn
      2. Domain d1j36b1: 1j36 B:23-615 [84055]
        Other proteins in same PDB: d1j36a2, d1j36b2
        complexed with lpr, zn
    2. Domains for 1j37:
      1. Domain d1j37a1: 1j37 A:23-615 [84056]
        Other proteins in same PDB: d1j37a2, d1j37b2
        complexed with x8z, zn
      2. Domain d1j37b1: 1j37 B:23-615 [84057]
        Other proteins in same PDB: d1j37a2, d1j37b2
        complexed with x8z, zn
    3. Domains for 1j38:
      1. Domain d1j38a1: 1j38 A:23-615 [84058]
        Other proteins in same PDB: d1j38a2, d1j38b2
        complexed with zn
      2. Domain d1j38b1: 1j38 B:23-615 [84059]
        Other proteins in same PDB: d1j38a2, d1j38b2
        complexed with zn
  2. Human (Homo sapiens) [TaxId:9606] [82734] (15 PDB entries)
    Uniprot P22966
    1. Domain for 1o86:
    2. Domain for 1o8a:
    3. Domain for 1uze:
    4. Domain for 1uzf:
    5. Domain for 2oc2:
    6. Domain for 2xy9:
    7. Domain for 3bkk:
    8. Domain for 3bkl:
    9. Domain for 3l3n:
    10. Domain for 4bzr:
    11. Domain for 4ca5:
    12. Domain for 6f9t:
    13. Domain for 6f9u:
      • Domain d6f9ua_: 6f9u A: [350665]
        automated match to d4c2oa_
        complexed with 1pe, bo3, cl, d0w, edo, imd, nag, peg, zn
    14. Domain for 6h5w:
    15. Domain for 6zpu:

More info for Protein Angiotensin converting enzyme, ACE from d.92.1.5: Neurolysin-like

Timeline for Protein Angiotensin converting enzyme, ACE from d.92.1.5: Neurolysin-like: