SCOPe 2.03: Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH

Lineage for Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (23 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH [82568] (6 proteins)
   Pfam PF00443

Proteins:

1. Ubiquitin carboxyl-terminal hydrolase 14 [142860] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [142861] (2 PDB entries)
     Uniprot P54578 100-482

2. Ubiquitin carboxyl-terminal hydrolase 2, USP2 [159841] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [159842] (2 PDB entries)
     Uniprot O75604 263-600! Uniprot O75604 264-599

3. Ubiquitin carboxyl-terminal hydrolase 6 [110769] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [110770] (1 PDB entry)
     Uniprot P43593 103-499

4. Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP) [82569] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [82570] (2 PDB entries)

5. Ubiquitin carboxyl-terminal hydrolase 8 [142858] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [142859] (2 PDB entries)
     Uniprot P40818 762-1109

6. automated matches [191167] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [189384] (5 PDB entries)

More info for Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH

Timeline for Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH:

• Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH first appeared in SCOP 1.63, called Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP)
  
• Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH appears in SCOPe 2.02
  
• Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH appears in SCOPe 2.04
  
• Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH appears in the current release, SCOPe 2.08