Class c: Alpha and beta proteins (a/b) [51349] (136 folds) |
Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily) consists of two intertwined (sub)domains related by pseudo dyad; duplication 3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest |
Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (5 families) the constituent families form similar dimers |
Family c.77.1.2: Monomeric isocitrate dehydrogenase [82526] (1 protein) the active site is contained within one subunit between the canonical ICDH fold and a large insert domain that itself is a probable rudiment form of ICDH fold resulted from duplication, domain swapping and deletion |
Protein Monomeric isocitrate dehydrogenase [82527] (1 species) |
Species Azotobacter vinelandii [TaxId:354] [82528] (1 PDB entry) the insert region spans residues 150-404 |
Domain d1itwa_: 1itw A: [76793] |
Domain d1itwb_: 1itw B: [76794] |
Domain d1itwc_: 1itw C: [76795] |
Domain d1itwd_: 1itw D: [76796] |
Timeline for Species Azotobacter vinelandii [TaxId:354] from c.77.1.2 Monomeric isocitrate dehydrogenase: