Lineage for Family c.77.1.2: Monomeric isocitrate dehydrogenase

  1. Root: SCOPe 2.01
  2. 968085Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1005388Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 1005389Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) (S)
    the constituent families form similar dimers
  5. 1005547Family c.77.1.2: Monomeric isocitrate dehydrogenase [82526] (2 proteins)
    the active site is contained within one subunit between the canonical ICDH fold and a large insert domain that itself is a probable rudiment form of ICDH fold resulted from duplication, domain swapping and deletion


  1. 1005548Monomeric isocitrate dehydrogenase [82527] (1 species)
  2. 1005554automated matches [190493] (2 species)
    not a true protein
    1. 1005555Species Corynebacterium glutamicum [TaxId:1718] [187435] (1 PDB entry)
    2. 1005557Species Corynebacterium glutamicum [TaxId:196627] [189781] (1 PDB entry)

More info for Family c.77.1.2: Monomeric isocitrate dehydrogenase

Timeline for Family c.77.1.2: Monomeric isocitrate dehydrogenase: