Lineage for Family c.77.1.2: Monomeric isocitrate dehydrogenase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2138632Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 2138633Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) (S)
    the constituent families form similar dimers
  5. 2138891Family c.77.1.2: Monomeric isocitrate dehydrogenase [82526] (2 protein domains)
    the active site is contained within one subunit between the canonical ICDH fold and a large insert domain that itself is a probable rudiment form of ICDH fold resulted from duplication, domain swapping and deletion
    automatically mapped to Pfam PF03971

Protein Domains:

  1. 2138892Monomeric isocitrate dehydrogenase [82527] (1 species)
  2. 2138898automated matches [190493] (4 species)
    not a true protein
    1. 2138899Species Corynebacterium glutamicum [TaxId:1718] [187435] (1 PDB entry)
    2. 2138901Species Corynebacterium glutamicum [TaxId:196627] [189781] (1 PDB entry)
    3. 2275822Species Mycobacterium smegmatis [TaxId:1772] [319123] (1 PDB entry)
    4. 2293501Species Mycobacterium tuberculosis [TaxId:83332] [336802] (1 PDB entry)

More info for Family c.77.1.2: Monomeric isocitrate dehydrogenase

Timeline for Family c.77.1.2: Monomeric isocitrate dehydrogenase: