SCOP 1.63: Protein: NADP-dependent isocitrate dehydrogenase

Lineage for Protein: NADP-dependent isocitrate dehydrogenase

Root: SCOP 1.63
Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

Fold c.77: Isocitrate/Isopropylmalate dehydrogenases [53658] (1 superfamily)
consists of two intertwined (sub)domains related by pseudodyad; duplication
3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenases [53659] (2 families)
Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (3 proteins)
the active site is between the two identical subunits
Protein NADP-dependent isocitrate dehydrogenase [82524] (1 species)

Species:

Pig (Sus scrofa) [TaxId:9823] [82525] (1 PDB entry)
- Domains for 1lwd:
  1. Domain d1lwda_: 1lwd A: [78265]
  2. Domain d1lwdb_: 1lwd B: [78266]
    complexed with ict, mn, so4

More info for Protein NADP-dependent isocitrate dehydrogenase from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases

Timeline for Protein NADP-dependent isocitrate dehydrogenase from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases:

Protein NADP-dependent isocitrate dehydrogenase from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases is new in SCOP 1.63
Protein NADP-dependent isocitrate dehydrogenase from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases appears in SCOP 1.65
Protein NADP-dependent isocitrate dehydrogenase from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases appears in the current release, SCOPe 2.08