SCOP 1.69: Family c.43.1.3: Choline/Carnitine O-acyltransferase (Pfam 00755)

Lineage for Family c.43.1.3: Choline/Carnitine O-acyltransferase (Pfam 00755)

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.43: CoA-dependent acyltransferases [52776] (1 superfamily)
   core: 2 layers, a/b; mixed beta-sheet of 6 strands, order 324561; strands 3 & 6 are antiparallel to the rest

4. Superfamily c.43.1: CoA-dependent acyltransferases [52777] (3 families)

5. Family c.43.1.3: Choline/Carnitine O-acyltransferase (Pfam 00755) [82424] (2 proteins)
   monomeric enzyme containing tandem repeat of two CAT subunit-like domains

Proteins:

1. Carnitine acetyltransferase [82425] (2 species)
   relative spatial position of the domains is similar to the monomers in CAT trimer

   1. Species Human (Homo sapiens) [TaxId:9606] [89697] (2 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [82426] (6 PDB entries)

2. Choline O-acetyltransferase [110591] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [110592] (1 PDB entry)

More info for Family c.43.1.3: Choline/Carnitine O-acyltransferase (Pfam 00755)

Timeline for Family c.43.1.3: Choline/Carnitine O-acyltransferase (Pfam 00755):

• Family c.43.1.3: Choline/Carnitine O-acyltransferase (Pfam 00755) first appeared in SCOP 1.63, called Family c.43.1.3: Carnitine acetyltransferase
  
• Family c.43.1.3: Choline/Carnitine O-acyltransferase (Pfam 00755) was called Family c.43.1.3: Carnitine acetyltransferase in SCOP 1.67
  
• Family c.43.1.3: Choline/Carnitine O-acyltransferase (Pfam 00755) is called Family c.43.1.3: Choline/Carnitine O-acyltransferase in SCOP 1.71
  
• Family c.43.1.3: Choline/Carnitine O-acyltransferase (Pfam 00755) appears in the current release, SCOPe 2.08, called Family c.43.1.3: Choline/Carnitine O-acyltransferase