Lineage for Family c.108.1.8: 5'(3')-deoxyribonucleotidase (dNT-2)

  1. Root: SCOP 1.69
  2. 473232Class c: Alpha and beta proteins (a/b) [51349] (136 folds)
  3. 495850Fold c.108: HAD-like [56783] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456
  4. 495851Superfamily c.108.1: HAD-like [56784] (16 families) (S)
    contains an insert alpha+beta subdomain; similar overall fold to the Cof family
    usually contains an insertion (sub)domain after strand 1
  5. 495962Family c.108.1.8: 5'(3')-deoxyribonucleotidase (dNT-2) [82382] (1 protein)
    the insertion subdomain is a 4-helical bundle; dephosphorylates dUMP and dTMP

Protein:

More info for Family c.108.1.8: 5'(3')-deoxyribonucleotidase (dNT-2)

Timeline for Family c.108.1.8: 5'(3')-deoxyribonucleotidase (dNT-2):