SCOPe 2.08: Protein: Betaine-homocysteine S-methyltransferase

Lineage for Protein: Betaine-homocysteine S-methyltransferase

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites

Superfamily c.1.26: Homocysteine S-methyltransferase [82282] (1 family)
Family c.1.26.1: Homocysteine S-methyltransferase [82283] (2 proteins)
Pfam PF02574
Protein Betaine-homocysteine S-methyltransferase [82284] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [82285] (3 PDB entries)
1. Domains for 1lt7:
  1. Domain d1lt7a_: 1lt7 A: [78184]
    complexed with cit, sm
  2. Domain d1lt7b_: 1lt7 B: [78185]
    complexed with cit, sm
2. Domains for 1lt8:
  1. Domain d1lt8a_: 1lt8 A: [78186]
    complexed with cbh, cit, zn
  2. Domain d1lt8b_: 1lt8 B: [78187]
    complexed with cbh, cit, zn
3. Domains for 4m3p:
  1. Domain d4m3pa_: 4m3p A: [257073]
    automated match to d1umyc_
    complexed with hcs, k, srt, zn
  2. Domain d4m3pb_: 4m3p B: [263000]
    automated match to d1umyc_
    complexed with hcs, k, srt, zn
  3. Domain d4m3pc_: 4m3p C: [260171]
    automated match to d1umyc_
    complexed with hcs, k, srt, zn
  4. Domain d4m3pd_: 4m3p D: [263001]
    automated match to d1umyc_
    complexed with hcs, k, srt, zn
Norway rat (Rattus norvegicus) [TaxId:10116] [102107] (1 PDB entry)
- Domains for 1umy:
  1. Domain d1umya_: 1umy A: [99635]
    complexed with bme, zn
  2. Domain d1umyb_: 1umy B: [99636]
    complexed with bme, zn
  3. Domain d1umyc_: 1umy C: [99637]
    complexed with bme, zn
  4. Domain d1umyd_: 1umy D: [99638]
    complexed with bme, zn

More info for Protein Betaine-homocysteine S-methyltransferase from c.1.26.1: Homocysteine S-methyltransferase

Timeline for Protein Betaine-homocysteine S-methyltransferase from c.1.26.1: Homocysteine S-methyltransferase:

Protein Betaine-homocysteine S-methyltransferase from c.1.26.1: Homocysteine S-methyltransferase first appeared in SCOP 1.63, called Protein Betaine-homocysteine S-methyltransferase from c.1.26.1: Betaine-homocysteine S-methyltransferase
Protein Betaine-homocysteine S-methyltransferase from c.1.26.1: Homocysteine S-methyltransferase appears in SCOPe 2.07