SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family c.1.26.1: Homocysteine S-methyltransferase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2090074Superfamily c.1.26: Homocysteine S-methyltransferase [82282] (1 family) (S)
  5. 2090075Family c.1.26.1: Homocysteine S-methyltransferase [82283] (3 protein domains)
    Pfam PF02574

Protein Domains:

  1. 2090076Betaine-homocysteine S-methyltransferase [82284] (2 species)
    1. 2090077Species Human (Homo sapiens) [TaxId:9606] [82285] (2 PDB entries)
    2. 2090082Species Norway rat (Rattus norvegicus) [TaxId:10116] [102107] (1 PDB entry)
  2. 2090087Cobalamin-dependent methionine synthase MetH, N-terminal domain [102108] (1 species)
    5-methyltetrahydrofolate homocysteine S-methyltransferase
  3. 2090105automated matches [257071] (1 species)
    not a true protein

More info for Family c.1.26.1: Homocysteine S-methyltransferase

Timeline for Family c.1.26.1: Homocysteine S-methyltransferase: