Lineage for Protein: Epididymal secretory protein E1 (Niemann-Pick C2 protein)
- Root: SCOPe 2.08
Class b: All beta proteins [48724] (180 folds) 
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strandsSuperfamily b.1.18: E set domains [81296] (27 families) 
"Early" Ig-like fold families possibly related to the immunoglobulin and/or fibronectin type III superfamilies
Family b.1.18.7: ML domain [81287] (3 proteins)
implicated in lipid recognition, particularly in the recognition of pathogen related products
automatically mapped to Pfam PF02221Protein Epididymal secretory protein E1 (Niemann-Pick C2 protein) [81964] (1 species)
a cholesterol binding protein
Species:
Cow (Bos taurus) [TaxId:9913] [81965] (2 PDB entries) - Domain for 1nep:
Domain d1nepa_: 1nep A: [80440]
complexed with nag, po4
- Domains for 2hka:
Domain d2hkaa_: 2hka A: [147298]
automated match to d1nepa_
complexed with act, c3s, gol, nag, so4
Domain d2hkab_: 2hka B: [147299]
automated match to d1nepa_
complexed with act, c3s, gol, nag, so4
Domain d2hkac_: 2hka C: [147300]
automated match to d1nepa_
complexed with act, c3s, gol, nag, so4
- Domain for 1nep:
More info for Protein Epididymal secretory protein E1 (Niemann-Pick C2 protein) from b.1.18.7: ML domain
Timeline for Protein Epididymal secretory protein E1 (Niemann-Pick C2 protein) from b.1.18.7: ML domain:
- Protein Epididymal secretory protein E1 (Niemann-Pick C2 protein) from b.1.18.7: ML domain first appeared in SCOP 1.63
- Protein Epididymal secretory protein E1 (Niemann-Pick C2 protein) from b.1.18.7: ML domain appears in SCOPe 2.07