SCOP 1.69: Family f.21.2.2: Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD)

Lineage for Family f.21.2.2: Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD)

1. Root: SCOP 1.69

2. Class f: Membrane and cell surface proteins and peptides [56835] (47 folds)

3. Fold f.21: Heme-binding four-helical bundle [81344] (3 superfamilies)
   core: four transmembrane helices, up-and-down bundle, binds one or two heme groups in between the helices

4. Superfamily f.21.2: Fumarate reductase respiratory complex transmembrane subunits [81343] (2 families)
   two distinct families: in one family the common fold is contained in a single-chain subunit, in the other it is formed by two chains

5. Family f.21.2.2: Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) [81373] (4 proteins)
   consists of two homologous non-identical subunits that form a heterodimer; may or may not contain heme groups

Proteins:

1. Fumarate reductase subunit FrdC [81370] (1 species)

   • Species Escherichia coli [TaxId:562] [81369] (3 PDB entries)
     is not known to bind heme

2. Fumarate reductase subunit FrdD [81372] (1 species)

   • Species Escherichia coli [TaxId:562] [81371] (3 PDB entries)
     is not known to bind heme

3. Succinate dehydrogenase subunit SdhC [82870] (1 species)
   Cytochrome b556 subunit

   • Species Escherichia coli [TaxId:562] [82871] (2 PDB entries)

4. Succinate dehydrogenase subunit SdhD [82872] (1 species)
   membrane anchor protein

   • Species Escherichia coli [TaxId:562] [82873] (2 PDB entries)

More info for Family f.21.2.2: Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD)

Timeline for Family f.21.2.2: Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD):

• Family f.21.2.2: Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) first appeared in SCOP 1.63
  
• Family f.21.2.2: Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) appears in SCOP 1.67
  
• Family f.21.2.2: Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) appears in SCOP 1.71
  
• Family f.21.2.2: Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) appears in the current release, SCOPe 2.08