Lineage for Protein: Class sigma GST

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2712830Fold a.45: GST C-terminal domain-like [47615] (1 superfamily)
    core: 4 helices; bundle, closed, left-handed twist; right-handed superhelix
  4. 2712831Superfamily a.45.1: GST C-terminal domain-like [47616] (3 families) (S)
    this domains follows the thioredoxin-like N-terminal domain
  5. 2712832Family a.45.1.1: Glutathione S-transferase (GST), C-terminal domain [47617] (19 proteins)
  6. 2713389Protein Class sigma GST [81351] (5 species)

Species:

  1. 2713390Fruit fly (Drosophila melanogaster) [TaxId:7227] [81771] (1 PDB entry)
  2. 2713393Heligmosomoides polygyrus [TaxId:6339] [109834] (1 PDB entry)
    Uniprot Q9NJQ6 # Fragment
  3. 2713402Human (Homo sapiens) [TaxId:9606] [89061] (16 PDB entries)
    Uniprot O60760; synonym: hematopoietic prostaglandin D synthase
    1. Domains for 1iyh:
      1. 2713425Domain d1iyha1: 1iyh A:76-199 [83790]
        Other proteins in same PDB: d1iyha2, d1iyhb2, d1iyhc2, d1iyhd2
        complexed with gsh, mg
      2. 2713426Domain d1iyhb1: 1iyh B:276-399 [83792]
        Other proteins in same PDB: d1iyha2, d1iyhb2, d1iyhc2, d1iyhd2
        complexed with gsh, mg
      3. 2713427Domain d1iyhc1: 1iyh C:476-599 [83794]
        Other proteins in same PDB: d1iyha2, d1iyhb2, d1iyhc2, d1iyhd2
        complexed with gsh, mg
      4. 2713428Domain d1iyhd1: 1iyh D:676-799 [83796]
        Other proteins in same PDB: d1iyha2, d1iyhb2, d1iyhc2, d1iyhd2
        complexed with gsh, mg
    2. Domains for 1iyi:
      1. 2713431Domain d1iyia1: 1iyi A:76-199 [83798]
        Other proteins in same PDB: d1iyia2, d1iyib2, d1iyic2, d1iyid2
        complexed with ca, gsh
      2. 2713432Domain d1iyib1: 1iyi B:276-399 [83800]
        Other proteins in same PDB: d1iyia2, d1iyib2, d1iyic2, d1iyid2
        complexed with ca, gsh
      3. 2713433Domain d1iyic1: 1iyi C:476-599 [83802]
        Other proteins in same PDB: d1iyia2, d1iyib2, d1iyic2, d1iyid2
        complexed with ca, gsh
      4. 2713434Domain d1iyid1: 1iyi D:676-799 [83804]
        Other proteins in same PDB: d1iyia2, d1iyib2, d1iyic2, d1iyid2
        complexed with ca, gsh
    3. Domains for 1v40:
      1. 2713413Domain d1v40a1: 1v40 A:76-199 [113512]
        Other proteins in same PDB: d1v40a2, d1v40b2, d1v40c2, d1v40d2
        complexed with gol, gsh, mg, o16
      2. 2713414Domain d1v40b1: 1v40 B:276-399 [113514]
        Other proteins in same PDB: d1v40a2, d1v40b2, d1v40c2, d1v40d2
        complexed with gol, gsh, mg, o16
      3. 2713415Domain d1v40c1: 1v40 C:476-599 [113516]
        Other proteins in same PDB: d1v40a2, d1v40b2, d1v40c2, d1v40d2
        complexed with gol, gsh, mg, o16
      4. 2713416Domain d1v40d1: 1v40 D:676-799 [113518]
        Other proteins in same PDB: d1v40a2, d1v40b2, d1v40c2, d1v40d2
        complexed with gol, gsh, mg, o16
    4. Domains for 2cvd:
      1. 2713405Domain d2cvda1: 2cvd A:76-199 [130861]
        Other proteins in same PDB: d2cvda2, d2cvdb2, d2cvdc2, d2cvdd2
        automated match to d1iyha1
        complexed with gol, gsh, hql, mg
      2. 2713406Domain d2cvdb1: 2cvd B:76-199 [130863]
        Other proteins in same PDB: d2cvda2, d2cvdb2, d2cvdc2, d2cvdd2
        automated match to d1iyha1
        complexed with gol, gsh, hql, mg
      3. 2713407Domain d2cvdc1: 2cvd C:76-199 [130865]
        Other proteins in same PDB: d2cvda2, d2cvdb2, d2cvdc2, d2cvdd2
        automated match to d1iyha1
        complexed with gol, gsh, hql, mg
      4. 2713408Domain d2cvdd1: 2cvd D:76-199 [130867]
        Other proteins in same PDB: d2cvda2, d2cvdb2, d2cvdc2, d2cvdd2
        automated match to d1iyha1
        complexed with gol, gsh, hql, mg
    5. Domains for 3ee2:
      1. 2713448Domain d3ee2a1: 3ee2 A:76-199 [158117]
        Other proteins in same PDB: d3ee2a2, d3ee2b2
        automated match to d1pd211
        complexed with gsh, mg, nzo
      2. 2713449Domain d3ee2b1: 3ee2 B:76-199 [158119]
        Other proteins in same PDB: d3ee2a2, d3ee2b2
        automated match to d1pd211
        complexed with gsh, mg, nzo
    6. Domains for 3vi5:
      1. 2713421Domain d3vi5a2: 3vi5 A:76-199 [217829]
        Other proteins in same PDB: d3vi5a1, d3vi5b1, d3vi5c1, d3vi5d1
        automated match to d1iyha1
        complexed with ca, gol, gsh, m4m
      2. 2713422Domain d3vi5b2: 3vi5 B:276-399 [217831]
        Other proteins in same PDB: d3vi5a1, d3vi5b1, d3vi5c1, d3vi5d1
        automated match to d1iyha1
        complexed with ca, gol, gsh, m4m
      3. 2713423Domain d3vi5c2: 3vi5 C:476-599 [217833]
        Other proteins in same PDB: d3vi5a1, d3vi5b1, d3vi5c1, d3vi5d1
        automated match to d1iyha1
        complexed with ca, gol, gsh, m4m
      4. 2713424Domain d3vi5d2: 3vi5 D:676-799 [217835]
        Other proteins in same PDB: d3vi5a1, d3vi5b1, d3vi5c1, d3vi5d1
        automated match to d1iyha1
        complexed with ca, gol, gsh, m4m
    7. Domains for 3vi7:
      1. 2713417Domain d3vi7a2: 3vi7 A:76-199 [217837]
        Other proteins in same PDB: d3vi7a1, d3vi7b1, d3vi7c1, d3vi7d1
        automated match to d1iyha1
        complexed with ca, cbd, gsh
      2. 2713418Domain d3vi7b2: 3vi7 B:276-399 [217839]
        Other proteins in same PDB: d3vi7a1, d3vi7b1, d3vi7c1, d3vi7d1
        automated match to d1iyha1
        complexed with ca, cbd, gsh
      3. 2713419Domain d3vi7c2: 3vi7 C:476-599 [217841]
        Other proteins in same PDB: d3vi7a1, d3vi7b1, d3vi7c1, d3vi7d1
        automated match to d1iyha1
        complexed with ca, cbd, gsh
      4. 2713420Domain d3vi7d2: 3vi7 D:676-799 [217843]
        Other proteins in same PDB: d3vi7a1, d3vi7b1, d3vi7c1, d3vi7d1
        automated match to d1iyha1
        complexed with ca, cbd, gsh
    8. Domains for 5ywe:
      1. 2713438Domain d5ywea2: 5ywe A:76-199 [360983]
        Other proteins in same PDB: d5ywea1, d5yweb1, d5ywec1, d5ywed1
        automated match to d2cvda1
        complexed with gol, gsh, mg
      2. 2713439Domain d5yweb2: 5ywe B:76-199 [360967]
        Other proteins in same PDB: d5ywea1, d5yweb1, d5ywec1, d5ywed1
        automated match to d2cvda1
        complexed with gol, gsh, mg
      3. 2713440Domain d5ywec2: 5ywe C:76-199 [360953]
        Other proteins in same PDB: d5ywea1, d5yweb1, d5ywec1, d5ywed1
        automated match to d2cvda1
        complexed with gol, gsh, mg
      4. 2713441Domain d5ywed2: 5ywe D:76-199 [360927]
        Other proteins in same PDB: d5ywea1, d5yweb1, d5ywec1, d5ywed1
        automated match to d2cvda1
        complexed with gol, gsh, mg
    9. Domains for 5ywx:
      1. 2713444Domain d5ywxa2: 5ywx A:76-199 [357214]
        Other proteins in same PDB: d5ywxa1, d5ywxb1, d5ywxc1, d5ywxd1
        automated match to d2cvda1
        complexed with 93c, gol, gsh, mg
      2. 2713445Domain d5ywxb2: 5ywx B:76-199 [357183]
        Other proteins in same PDB: d5ywxa1, d5ywxb1, d5ywxc1, d5ywxd1
        automated match to d2cvda1
        complexed with 93c, gol, gsh, mg
      3. 2713446Domain d5ywxc2: 5ywx C:76-199 [357138]
        Other proteins in same PDB: d5ywxa1, d5ywxb1, d5ywxc1, d5ywxd1
        automated match to d2cvda1
        complexed with 93c, gol, gsh, mg
      4. 2713447Domain d5ywxd2: 5ywx D:76-199 [357205]
        Other proteins in same PDB: d5ywxa1, d5ywxb1, d5ywxc1, d5ywxd1
        automated match to d2cvda1
        complexed with 93c, gol, gsh, mg
    10. Domains for 5yx1:
      1. 2713409Domain d5yx1a2: 5yx1 A:76-199 [360885]
        Other proteins in same PDB: d5yx1a1, d5yx1b1, d5yx1c1, d5yx1d1
        automated match to d2cvda1
        complexed with gol, gsh, mg, ux4
      2. 2713410Domain d5yx1b2: 5yx1 B:76-199 [360955]
        Other proteins in same PDB: d5yx1a1, d5yx1b1, d5yx1c1, d5yx1d1
        automated match to d2cvda1
        complexed with gol, gsh, mg, ux4
      3. 2713411Domain d5yx1c2: 5yx1 C:76-199 [360957]
        Other proteins in same PDB: d5yx1a1, d5yx1b1, d5yx1c1, d5yx1d1
        automated match to d2cvda1
        complexed with gol, gsh, mg, ux4
      4. 2713412Domain d5yx1d2: 5yx1 D:76-199 [360938]
        Other proteins in same PDB: d5yx1a1, d5yx1b1, d5yx1c1, d5yx1d1
        automated match to d2cvda1
        complexed with gol, gsh, mg, ux4
    11. Domain for 6n4e:
    12. Domains for 6w58:
      1. 2713450Domain d6w58a2: 6w58 A:76-199 [396115]
        Other proteins in same PDB: d6w58a1, d6w58b1
        automated match to d1pd211
        complexed with gsh, sws
      2. 2713451Domain d6w58b2: 6w58 B:76-199 [396132]
        Other proteins in same PDB: d6w58a1, d6w58b1
        automated match to d1pd211
        complexed with gsh, sws
    13. Domains for 6w8h:
      1. 2713442Domain d6w8ha2: 6w8h A:76-199 [396102]
        Other proteins in same PDB: d6w8ha1, d6w8hc1
        automated match to d1pd211
        complexed with edo, gsh, tjg
      2. 2713443Domain d6w8hc2: 6w8h C:76-199 [396104]
        Other proteins in same PDB: d6w8ha1, d6w8hc1
        automated match to d1pd211
        complexed with edo, gsh, tjg
    14. Domains for 6ztc:
      1. 2713429Domain d6ztca2: 6ztc A:76-199 [417433]
        Other proteins in same PDB: d6ztca1, d6ztcb1, d6ztcb3
        automated match to d5y9za2
        complexed with gol, gsh, mg, qpn
      2. 2713430Domain d6ztcb2: 6ztc B:76-199 [417435]
        Other proteins in same PDB: d6ztca1, d6ztcb1, d6ztcb3
        automated match to d5y9za2
        complexed with gol, gsh, mg, qpn
    15. Domains for 7jr6:
      1. 2713435Domain d7jr6a2: 7jr6 A:76-199 [405326]
        Other proteins in same PDB: d7jr6a1, d7jr6a3, d7jr6b1, d7jr6b3
        automated match to d1pd211
        complexed with gsh, mg, na, vh4
      2. 2713436Domain d7jr6b2: 7jr6 B:76-199 [405337]
        Other proteins in same PDB: d7jr6a1, d7jr6a3, d7jr6b1, d7jr6b3
        automated match to d1pd211
        complexed with gsh, mg, na, vh4
    16. Domains for 7jr8:
      1. 2713403Domain d7jr8a2: 7jr8 A:76-199 [405367]
        Other proteins in same PDB: d7jr8a1, d7jr8a3, d7jr8b1, d7jr8b3
        automated match to d1pd211
        complexed with cl, edo, gsh, mg, na, vh7
      2. 2713404Domain d7jr8b2: 7jr8 B:76-199 [405364]
        Other proteins in same PDB: d7jr8a1, d7jr8a3, d7jr8b1, d7jr8b3
        automated match to d1pd211
        complexed with cl, edo, gsh, mg, na, vh7
  4. 2713452Norway rat (Rattus norvegicus) [TaxId:10116] [47630] (3 PDB entries)
    synonym: hematopoietic prostaglandin D synthase
    1. Domains for 1pd2:
      1. 2713457Domain d1pd211: 1pd2 1:76-199 [17713]
        Other proteins in same PDB: d1pd212, d1pd222
        complexed with gsh
      2. 2713458Domain d1pd221: 1pd2 2:76-199 [17714]
        Other proteins in same PDB: d1pd212, d1pd222
        complexed with gsh
    2. Domains for 5y9z:
      1. 2713453Domain d5y9za2: 5y9z A:76-199 [357865]
        Other proteins in same PDB: d5y9za1, d5y9zb1
        automated match to d1pd211
        complexed with dio, edo, gol, gsh, mg, pge
      2. 2713454Domain d5y9zb2: 5y9z B:76-199 [357831]
        Other proteins in same PDB: d5y9za1, d5y9zb1
        automated match to d1pd211
        complexed with dio, edo, gol, gsh, mg, pge
    3. Domains for 6n69:
      1. 2713455Domain d6n69a2: 6n69 A:76-199 [366929]
        Other proteins in same PDB: d6n69a1, d6n69b1
        automated match to d1pd211
        complexed with gsh, kdv
      2. 2713456Domain d6n69b2: 6n69 B:76-199 [366902]
        Other proteins in same PDB: d6n69a1, d6n69b1
        automated match to d1pd211
        complexed with gsh, kdv
  5. 2713459Squid (Ommastrephes sloani pacificus) [TaxId:6634] [47631] (2 PDB entries)
    1. Domain for 1gsq:
    2. Domain for 2gsq:

More info for Protein Class sigma GST from a.45.1.1: Glutathione S-transferase (GST), C-terminal domain

Timeline for Protein Class sigma GST from a.45.1.1: Glutathione S-transferase (GST), C-terminal domain: