SCOPe 2.05: Superfamily b.1.18: E set domains

Lineage for Superfamily b.1.18: E set domains

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.18: E set domains [81296] (24 families)
   "Early" Ig-like fold families possibly related to the immunoglobulin and/or fibronectin type III superfamilies

Families:

1. b.1.18.1: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain [81279] (8 proteins)
   subgroup of the larger IPT/TIG domain family

2. b.1.18.2: E-set domains of sugar-utilizing enzymes [81282] (20 proteins)
   domains of unknown function associated with different type of catalytic domains in a different sequential location
   subgroup of the larger IPT/TIG domain family

3. b.1.18.3: Arthropod hemocyanin, C-terminal domain [81283] (1 protein)
   automatically mapped to Pfam PF03723

4. b.1.18.4: Class II viral fusion proteins C-terminal domain [81284] (3 proteins)

5. b.1.18.5: Cytomegalovirus protein US2 [81285] (1 protein)
   automatically mapped to Pfam PF05963

6. b.1.18.6: Molybdenum-containing oxidoreductases-like dimerisation domain [81286] (1 protein)
   automatically mapped to Pfam PF03404

7. b.1.18.7: ML domain [81287] (2 proteins)
   implicated in lipid recognition, particularly in the recognition of pathogen related products
   automatically mapped to Pfam PF02221

8. b.1.18.8: RhoGDI-like [81288] (3 proteins)

9. b.1.18.9: Transglutaminase N-terminal domain [81289] (1 protein)

10. b.1.18.10: Filamin repeat (rod domain) [81290] (5 proteins)
    Pfam PF00630

11. b.1.18.11: Arrestin/Vps26-like [81291] (2 proteins)

12. b.1.18.12: Gingipain R (RgpB), C-terminal domain [81292] (1 protein)
    automatically mapped to Pfam PF03785

13. b.1.18.13: Cellulosomal scaffoldin protein CipC, module x2.1 [81293] (1 protein)
    automatically mapped to Pfam PF03442

14. b.1.18.14: Quinohemoprotein amine dehydrogenase A chain, domains 4 and 5 [81294] (1 protein)

15. b.1.18.15: Internalin Ig-like domain [81295] (3 proteins)
    truncated fold fused to an LRR domain

16. b.1.18.16: Cytoplasmic domain of inward rectifier potassium channel [81966] (4 proteins)

17. b.1.18.17: Copper resistance protein C (CopC, PcoC) [81969] (1 protein)
    automatically mapped to Pfam PF04234
    automatically mapped to Pfam PF13205

18. b.1.18.18: Other IPT/TIG domains [89191] (1 protein)
    apart from the domains of transcription factors and sugar-utilizing enzymes
    automatically mapped to Pfam PF01833

19. b.1.18.19: SoxZ-like [141027] (1 protein)
    automatically mapped to Pfam PF08770

20. b.1.18.20: Enterochelin esterase N-terminal domain-like [141030] (1 protein)
    PfamB PB013071
    automatically mapped to Pfam PF11806

21. b.1.18.21: AMPK-beta glycogen binding domain-like [158886] (4 proteins)
    lacks the N-terminal strand (A) and contains a beta-hairpin insertion in the C-terminal strand (G)

22. b.1.18.22: Sec63 C-terminal domain-like [158893] (1 protein)
    C-terminal part of Pfam PF02889

23. b.1.18.23: SVA-like [158896] (1 protein)
    Pfam PF05326

24. b.1.18.0: automated matches [191341] (1 protein)
    not a true family

More info for Superfamily b.1.18: E set domains

Timeline for Superfamily b.1.18: E set domains:

• Superfamily b.1.18: E set domains first appeared in SCOP 1.63
  
• Superfamily b.1.18: E set domains appears in SCOPe 2.04
  
• Superfamily b.1.18: E set domains appears in SCOPe 2.06
  
• Superfamily b.1.18: E set domains appears in the current release, SCOPe 2.08