Lineage for Family b.1.18.2: E-set domains of sugar-utilizing enzymes

  1. Root: SCOP 1.71
  2. 546417Class b: All beta proteins [48724] (149 folds)
  3. 546418Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 551984Superfamily b.1.18: E set domains [81296] (18 families) (S)
    "Early" Ig-like fold families possibly related to the immunoglobulin and/or fibronectin type III superfamilies
  5. 552070Family b.1.18.2: E-set domains of sugar-utilizing enzymes [81282] (18 proteins)
    domains of unknown function associated with different type of catalytic domains in a different sequential location
    subgroup of the larger IPT/TIG domain family

Proteins:

  1. 5520711,4-alpha-glucan branching enzyme, N-terminal domain N [81962] (1 species)
    domain architecture similar to isoamylase
  2. 552077Bacterial chitobiase (N-acetyl-beta-glucoseaminidase), C-terminal domain [49211] (1 species)
    rudiment form of Ig-like domain; follows the catalytic (beta/alpha)8-barrel domain; family 20 glycosyl hydrolases
  3. 552083CelD cellulase, N-terminal domain [49231] (1 species)
    precedes the catalytic alpha6/alpha6 domain
  4. 552086Cellulose 1,4-beta-cellobiosidase CbhA, precatalytic domain [101521] (1 species)
  5. 552090Chitin-binding protein CBP21 [117045] (1 species)
    member of Pfam 03067; elaborated fold with a large insertion between strands A and A'
  6. 552097Chitinase A, N-terminal domain N [49233] (1 species)
    precedes the catalytic (beta/alpha)8-barrel domain
  7. 552108Cyclomaltodextrin glycanotransferase, domain D [49215] (4 species)
    follows the starch-binding domain C; the catalytic domain A has (beta/alpha)8-barrel fold; family 13 glycosyl hydrolases
    1. 552109Species Bacillus circulans, different strains [TaxId:1397] [49216] (36 PDB entries)
    2. 552150Species Bacillus sp., strain 1011 [TaxId:1409] [49219] (8 PDB entries)
    3. 552167Species Bacillus stearothermophilus [TaxId:1422] [49217] (1 PDB entry)
    4. 552169Species Thermoanaerobacterium thermosulfurigenes, EM1 [TaxId:33950] [49220] (2 PDB entries)
  8. 552172Cyclomaltodextrinase, N-terminal domain [101523] (1 species)
    protein shares similar domain organization with maltogenic amylases but differs in the spatial arrangement of its domains
  9. 552176Five domain "maltogenic" alpha-amylase (glucan 1,4-alpha-maltohydrolase), domain D [81280] (1 species)
    domain architecture similar to cyclomaltodextrin glycosylhydrolases
  10. 552180Galactose oxidase, C-terminal domain [49209] (2 species)
    follows the catalytic seven-bladed beta-propeller domain
    1. 552181Species Dactylium dendroides [TaxId:5132] [49210] (4 PDB entries)
    2. 552186Species Fungi (Fusarium spp) [69164] (1 PDB entry)
      sequence identical to that of Dactylium dendroides
  11. 552188Glucans biosynthesis protein G (MdoG, OpgG), C-terminal domain [110054] (1 species)
  12. 552192Glucodextranase, domain B [101525] (1 species)
  13. 552196Glycosyltrehalose trehalohydrolase, N-terminal domain N [49224] (1 species)
    domain architecture similar to isoamylase
  14. 552200Hyaluronate lyase precatalytic domain [69167] (1 species)
    precedes the catalytic incomplete alpha5/alpha5 barrel
    a rudiment form of Ig-like domain
  15. 552205Isoamylase, N-terminal domain N [49226] (1 species)
    elaborated with a few large insertions in the common fold
    precedes the catalytic (beta/alpha)8-barrel domain, the domain architecture similar to maltogenic amylases
  16. 552208Maltogenic amylase, N-terminal domain N [49221] (4 species)
    precedes the catalytic (beta/alpha)8-barrel domain
    1. 552209Species Bacillus sp., cyclomaltodextrinase [TaxId:1409] [74842] (1 PDB entry)
    2. 552212Species Thermoactinomyces vulgaris, TVAI [TaxId:2026] [74843] (6 PDB entries)
    3. 552220Species Thermoactinomyces vulgaris, TVAII [TaxId:2026] [49223] (7 PDB entries)
    4. 552235Species Thermus sp. [TaxId:275] [49222] (2 PDB entries)
  17. 552240Neopullulanase, N-terminal domain [81960] (1 species)
    homologous to maltogenic amylase
  18. 552250Sialidase, "linker" domain [49237] (1 species)
    follows the catalytic six-bladed beta-propeller domain

More info for Family b.1.18.2: E-set domains of sugar-utilizing enzymes

Timeline for Family b.1.18.2: E-set domains of sugar-utilizing enzymes: