SCOP 1.69: Family b.1.18.2: E-set domains of sugar-utilizing enzymes

Lineage for Family b.1.18.2: E-set domains of sugar-utilizing enzymes

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.18: E set domains [81296] (18 families)
   "Early" Ig-like fold families possibly related to the immunoglobulin and/or fibronectin type III superfamilies

5. Family b.1.18.2: E-set domains of sugar-utilizing enzymes [81282] (17 proteins)
   domains of unknown function associated with different type of catalytic domains in a different sequential location
   subgroup of the larger IPT/TIG domain family

Proteins:

1. 1,4-alpha-glucan branching enzyme, N-terminal domain N [81962] (1 species)
   domain architecture similar to isoamylase

   • Species Escherichia coli [TaxId:562] [81963] (1 PDB entry)

2. Bacterial chitobiase (N-acetyl-beta-glucoseaminidase), C-terminal domain [49211] (1 species)
   rudiment form of Ig-like domain; follows the catalytic (beta/alpha)8-barrel domain; family 20 glycosyl hydrolases

   • Species Serratia marcescens [TaxId:615] [49212] (4 PDB entries)

3. CelD cellulase, N-terminal domain [49231] (1 species)
   precedes the catalytic alpha6/alpha6 domain

   • Species Clostridium thermocellum [TaxId:1515] [49232] (1 PDB entry)

4. Cellulose 1,4-beta-cellobiosidase CbhA, precatalytic domain [101521] (1 species)

   • Species Clostridium thermocellum [TaxId:1515] [101522] (2 PDB entries)

5. Chitinase A, N-terminal domain N [49233] (1 species)
   precedes the catalytic (beta/alpha)8-barrel domain

   • Species Serratia marcescens [TaxId:615] [49234] (8 PDB entries)

6. Cyclomaltodextrin glycanotransferase, domain D [49215] (4 species)
   follows the starch-binding domain C; the catalytic domain A has (beta/alpha)8-barrel fold; family 13 glycosyl hydrolases

   1. Species Bacillus circulans, different strains [TaxId:1397] [49216] (36 PDB entries)

   2. Species Bacillus sp., strain 1011 [TaxId:1409] [49219] (8 PDB entries)

   3. Species Bacillus stearothermophilus [TaxId:1422] [49217] (1 PDB entry)

   4. Species Thermoanaerobacterium thermosulfurigenes, EM1 [TaxId:33950] [49220] (2 PDB entries)

7. Cyclomaltodextrinase, N-terminal domain [101523] (1 species)
   protein shares similar domain organization with maltogenic amylases but differs in the spatial arrangement of its domains

   • Species Flavobacterium sp. 92 [TaxId:197856] [101524] (1 PDB entry)

8. Five domain "maltogenic" alpha-amylase (glucan 1,4-alpha-maltohydrolase), domain D [81280] (1 species)
   domain architecture similar to cyclomaltodextrin glycosylhydrolases

   • Species Bacillus stearothermophilus [TaxId:1422] [81281] (2 PDB entries)

9. Galactose oxidase, C-terminal domain [49209] (2 species)
   follows the catalytic seven-bladed beta-propeller domain

   1. Species Dactylium dendroides [TaxId:5132] [49210] (4 PDB entries)

   2. Species Fungi (Fusarium spp) [69164] (1 PDB entry)
      sequence identical to that of Dactylium dendroides

10. Glucans biosynthesis protein G (MdoG, OpgG), C-terminal domain [110054] (1 species)

    • Species Escherichia coli [TaxId:562] [110055] (1 PDB entry)

11. Glucodextranase, domain B [101525] (1 species)

    • Species Arthrobacter globiformis [TaxId:1665] [101526] (2 PDB entries)

12. Glycosyltrehalose trehalohydrolase, N-terminal domain N [49224] (1 species)
    domain architecture similar to isoamylase

    • Species Archaeon Sulfolobus solfataricus, km1 [TaxId:2287] [49225] (2 PDB entries)

13. Hyaluronate lyase precatalytic domain [69167] (1 species)
    precedes the catalytic incomplete alpha5/alpha5 barrel
    a rudiment form of Ig-like domain

    • Species Streptococcus agalactiae [TaxId:1311] [69168] (3 PDB entries)

14. Isoamylase, N-terminal domain N [49226] (1 species)
    elaborated with a few large insertions in the common fold
    precedes the catalytic (beta/alpha)8-barrel domain, the domain architecture similar to maltogenic amylases

    • Species Pseudomonas amyloderamosa [TaxId:32043] [49227] (1 PDB entry)

15. Maltogenic amylase, N-terminal domain N [49221] (4 species)
    precedes the catalytic (beta/alpha)8-barrel domain

    1. Species Bacillus sp., cyclomaltodextrinase [TaxId:1409] [74842] (1 PDB entry)

    2. Species Thermoactinomyces vulgaris, TVAI [TaxId:2026] [74843] (6 PDB entries)

    3. Species Thermoactinomyces vulgaris, TVAII [TaxId:2026] [49223] (7 PDB entries)

    4. Species Thermus sp. [TaxId:275] [49222] (2 PDB entries)

16. Neopullulanase, N-terminal domain [81960] (1 species)
    homologous to maltogenic amylase

    • Species Bacillus stearothermophilus [TaxId:1422] [81961] (4 PDB entries)

17. Sialidase, "linker" domain [49237] (1 species)
    follows the catalytic six-bladed beta-propeller domain

    • Species Micromonospora viridifaciens [TaxId:1881] [49238] (2 PDB entries)

More info for Family b.1.18.2: E-set domains of sugar-utilizing enzymes

Timeline for Family b.1.18.2: E-set domains of sugar-utilizing enzymes:

• Family b.1.18.2: E-set domains of sugar-utilizing enzymes first appeared in SCOP 1.63
  
• Family b.1.18.2: E-set domains of sugar-utilizing enzymes appears in SCOP 1.67
  
• Family b.1.18.2: E-set domains of sugar-utilizing enzymes appears in SCOP 1.71
  
• Family b.1.18.2: E-set domains of sugar-utilizing enzymes appears in the current release, SCOPe 2.08