SCOPe 2.01: Family b.1.18.1: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain

Lineage for Family b.1.18.1: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.18: E set domains [81296] (24 families)
   "Early" Ig-like fold families possibly related to the immunoglobulin and/or fibronectin type III superfamilies

5. Family b.1.18.1: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain [81279] (7 proteins)
   subgroup of the larger IPT/TIG domain family

Proteins:

1. Calmodulin binding transcription activator 1 [141017] (1 species)
   this domain is in the middle of long protein chain

   • Species Human (Homo sapiens) [TaxId:9606] [141018] (1 PDB entry)
     Uniprot Q9Y6Y1 872-953

2. DNA-binding protein LAG-1 (CSL) [110052] (1 species)

   • Species Nematode (Caenorhabditis elegans) [TaxId:6239] [110053] (4 PDB entries)
     Uniprot Q9TYY1 195-660

3. p50 subunit of NF-kappa B transcription factor [49248] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [49249] (9 PDB entries)
      Uniprot P25799 245-350

   2. Species Mouse (Mus musculus) [TaxId:10090] [49250] (10 PDB entries)

4. p52 subunit of NF-kappa B (NFKB) [49251] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [49252] (1 PDB entry)

5. p65 subunit of NF-kappa B (NFKB), dimerization domain [49253] (3 species)

   1. Species Chicken (Gallus gallus), C-rel [TaxId:9031] [74848] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [49255] (4 PDB entries)

   3. Species Mouse (Mus musculus) [TaxId:10090] [49254] (10 PDB entries)

6. T-cell transcription factor NFAT1 (NFATC2) [49246] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [49247] (7 PDB entries)

7. T-cell transcription factor NFAT5 (TONEBP) [69170] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [69171] (1 PDB entry)

More info for Family b.1.18.1: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain

Timeline for Family b.1.18.1: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain:

• Family b.1.18.1: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain first appeared in SCOP 1.63
  
• Family b.1.18.1: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain appears in SCOP 1.75
  
• Family b.1.18.1: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain appears in SCOPe 2.02
  
• Family b.1.18.1: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain appears in the current release, SCOPe 2.08