Lineage for Family c.37.1.20: Extended AAA-ATPase domain

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2113456Family c.37.1.20: Extended AAA-ATPase domain [81269] (29 protein domains)
    fold is similar to that of RecA, but lacks the last two strands, followed by a family-specific Arg-finger domain

Protein Domains:

  1. 2113457AAA domain of cell division protein FtsH [82418] (3 species)
    ATP-dependent protease
    1. 2113458Species Escherichia coli [TaxId:562] [82419] (1 PDB entry)
    2. 2113460Species Thermotoga maritima [TaxId:2336] [142325] (3 PDB entries)
      Uniprot Q9WZ49 150-402
    3. 2113476Species Thermus thermophilus [TaxId:274] [82420] (4 PDB entries)
  2. 2113481Archaeal ATPase SSO1545 [142326] (1 species)
    member of Pfam PF01637 family; overall structural similarity to the archael CDC6-like protein APE0102
  3. 2113485ATPase domain of protease Lon (La) [102393] (2 species)
    1. 2113486Species Brevibacillus thermoruber [TaxId:33942] [227843] (1 PDB entry)
    2. 2113489Species Escherichia coli [TaxId:562] [102394] (1 PDB entry)
  4. 2113491ATPase subunit of magnesium chelatase, BchI [64040] (1 species)
  5. 2113494CDC6, N-domain [52715] (1 species)
    contains "winged helix" DNA-binding domain after the family specific domains
  6. 2113498CDC6-like protein APE0152, N-terminal domain [117556] (1 species)
  7. 2113505CED-4, NB-ARC domain [159577] (1 species)
    belongs to Pfam PF00931
  8. 2113509Chromosomal replication initiation factor DnaA [82416] (1 species)
    contains TrpR-like DNA-binding domain after the family specific domains
  9. 2113516ClpA, an Hsp100 chaperone, AAA+ modules [82421] (1 species)
    duplication: two AAA+ modules; the first module is structurally similar to the CDC6 module whereas the second module to the HslU module
  10. 2113522ClpB, AAA+ modules [75211] (2 species)
    ATPase subunit of ATP-dependent protease; similar domain organization to ClpA
    1. 2113523Species Escherichia coli [TaxId:562] [75212] (1 PDB entry)
    2. 2113525Species Thermus thermophilus [TaxId:274] [102395] (1 PDB entry)
  11. 2113532ClpX [102391] (1 species)
    ATPase subunit of ATP-dependent protease
  12. 2113535delta prime subunit of DNA polymerase III, N-domain [52711] (1 species)
    contains additional alpha-helical domain after the family specific domains
  13. 2113549delta subunit of DNA polymerase III, N-domain [64033] (1 species)
  14. 2113559gamma subunit of DNA polymerase III, N-domain [64031] (2 species)
    1. 2113560Species Escherichia coli [TaxId:562] [64032] (3 PDB entries)
      Uniprot P06710 5-368
    2. 2113576Species Thermotoga maritima [TaxId:2336] [142324] (1 PDB entry)
      Uniprot Q9WZM9 11-208
  15. 2113578Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein [52717] (1 species)
  16. 2113582Holliday junction helicase RuvB [52713] (2 species)
    contains "winged helix" DNA-binding domain after the family specific domains
    1. 2113583Species Thermotoga maritima [TaxId:2336] [64037] (6 PDB entries)
    2. 2113590Species Thermus thermophilus [TaxId:274] [52714] (3 PDB entries)
  17. 2113595HslU [52721] (2 species)
    ATPase subunit of ATP-dependent protease
    1. 2113596Species Escherichia coli [TaxId:562] [52722] (11 PDB entries)
    2. 2113629Species Haemophilus influenzae [TaxId:727] [52723] (6 PDB entries)
  18. 2113662Membrane fusion ATPase VCP/p97 [64038] (2 species)
    1. 2113663Species Mouse (Mus musculus) [TaxId:10090] [64039] (4 PDB entries)
    2. 2270181Species Homo sapiens [TaxId:9606] [313486] (3 PDB entries)
  19. 2113679Papillomavirus large T antigen helicase domain [89688] (1 species)
  20. 2113706Rep 40 protein helicase domain [110564] (1 species)
  21. 2113712Replication factor C [64035] (1 species)
    contains additional alpha-helical domain after the family specific domains
  22. 2113720Replication factor C1 [110566] (1 species)
  23. 2113723Replication factor C2 [110572] (1 species)
  24. 2113726Replication factor C3 [110570] (1 species)
  25. 2113729Replication factor C4 [110568] (1 species)
  26. 2113732Replication factor C5 [110574] (1 species)
  27. 2113735Replication protein E1 helicase domain [110576] (1 species)
  28. 2113743Transcriptional activator sigm54 (NtrC1), C-terminal domain [102389] (1 species)
  29. 2113761automated matches [190766] (4 species)
    not a true protein
    1. 2113762Species Aquifex aeolicus [TaxId:63363] [226012] (1 PDB entry)
    2. 2113770Species Human (Homo sapiens) [TaxId:9606] [255867] (6 PDB entries)
    3. 2113805Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [187983] (1 PDB entry)
    4. 2276462Species Jc polyomavirus [TaxId:10632] [319763] (4 PDB entries)

More info for Family c.37.1.20: Extended AAA-ATPase domain

Timeline for Family c.37.1.20: Extended AAA-ATPase domain: