Lineage for Family c.37.1.20: Extended AAA-ATPase domain

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2446887Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2446888Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2451366Family c.37.1.20: Extended AAA-ATPase domain [81269] (42 protein domains)
    fold is similar to that of RecA, but lacks the last two strands, followed by a family-specific Arg-finger domain

Protein Domains:

  1. 2451367AAA domain of cell division protein FtsH [82418] (3 species)
    ATP-dependent protease
    1. 2451368Species Escherichia coli [TaxId:562] [82419] (1 PDB entry)
    2. 2451370Species Thermotoga maritima [TaxId:2336] [142325] (3 PDB entries)
      Uniprot Q9WZ49 150-402
    3. 2451386Species Thermus thermophilus [TaxId:274] [82420] (4 PDB entries)
  2. 2451391Archaeal ATPase SSO1545 [142326] (1 species)
    member of Pfam PF01637 family; overall structural similarity to the archael CDC6-like protein APE0102
  3. 2451395ATPase domain of protease Lon (La) [102393] (2 species)
    1. 2451396Species Brevibacillus thermoruber [TaxId:33942] [227843] (1 PDB entry)
    2. 2451399Species Escherichia coli [TaxId:562] [102394] (1 PDB entry)
  4. 2451401ATPase subunit of magnesium chelatase, BchI [64040] (1 species)
  5. 2451404CDC6, N-domain [52715] (1 species)
    contains "winged helix" DNA-binding domain after the family specific domains
  6. 2451408CDC6-like protein APE0152, N-terminal domain [117556] (1 species)
  7. 2451415CED-4, NB-ARC domain [159577] (1 species)
    belongs to Pfam PF00931
  8. 2451419Chromosomal replication initiation factor DnaA [82416] (1 species)
    contains TrpR-like DNA-binding domain after the family specific domains
  9. 2451426ClpA, an Hsp100 chaperone, AAA+ modules [82421] (1 species)
    duplication: two AAA+ modules; the first module is structurally similar to the CDC6 module whereas the second module to the HslU module
  10. 2451432ClpB, AAA+ modules [75211] (2 species)
    ATPase subunit of ATP-dependent protease; similar domain organization to ClpA
    1. 2451433Species Escherichia coli [TaxId:562] [75212] (1 PDB entry)
    2. 2451435Species Thermus thermophilus [TaxId:274] [102395] (1 PDB entry)
  11. 2451442ClpX [102391] (1 species)
    ATPase subunit of ATP-dependent protease
  12. 2451445delta prime subunit of DNA polymerase III, N-domain [52711] (1 species)
    contains additional alpha-helical domain after the family specific domains
  13. 2451459delta subunit of DNA polymerase III, N-domain [64033] (1 species)
  14. 2451469gamma subunit of DNA polymerase III, N-domain [64031] (2 species)
    1. 2451470Species Escherichia coli [TaxId:562] [64032] (3 PDB entries)
      Uniprot P06710 5-368
    2. 2451486Species Thermotoga maritima [TaxId:2336] [142324] (1 PDB entry)
      Uniprot Q9WZM9 11-208
  15. 2451488Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein [52717] (1 species)
  16. 2451492Holliday junction helicase RuvB [52713] (2 species)
    contains "winged helix" DNA-binding domain after the family specific domains
    1. 2451493Species Thermotoga maritima [TaxId:2336] [64037] (6 PDB entries)
    2. 2451500Species Thermus thermophilus [TaxId:274] [52714] (3 PDB entries)
  17. 2451505HslU [52721] (2 species)
    ATPase subunit of ATP-dependent protease
    1. 2451506Species Escherichia coli [TaxId:562] [52722] (11 PDB entries)
    2. 2451540Species Haemophilus influenzae [TaxId:727] [52723] (6 PDB entries)
  18. 2451573Membrane fusion ATPase VCP/p97 [64038] (2 species)
    1. 2451574Species Human (Homo sapiens) [TaxId:9606] [313486] (4 PDB entries)
    2. 2451601Species Mouse (Mus musculus) [TaxId:10090] [64039] (4 PDB entries)
  19. 2451617Papillomavirus large T antigen helicase domain [89688] (1 species)
  20. 2451644Proteasome regulatory particle base subunit Rpt1, C-terminal domain [346072] (1 species)
  21. 2451647Proteasome regulatory particle base subunit Rpt1, OB-fold domain [346073] (1 species)
  22. 2451650Proteasome regulatory particle base subunit Rpt2, C-terminal domain [346074] (1 species)
  23. 2451653Proteasome regulatory particle base subunit Rpt2, OB-fold domain [346075] (1 species)
  24. 2451656Proteasome regulatory particle base subunit Rpt3, C-terminal domain [346076] (1 species)
  25. 2451659Proteasome regulatory particle base subunit Rpt3, OB-fold domain [346077] (1 species)
  26. 2451662Proteasome regulatory particle base subunit Rpt4, C-terminal domain [346078] (1 species)
  27. 2451665Proteasome regulatory particle base subunit Rpt4, OB-fold domain [346079] (1 species)
  28. 2451668Proteasome regulatory particle base subunit Rpt5, C-terminal domain [346080] (1 species)
  29. 2451671Proteasome regulatory particle base subunit Rpt5, OB-fold domain [346081] (1 species)
  30. 2451674Proteasome regulatory particle base subunit Rpt6, C-terminal domain [346082] (1 species)
  31. 2451677Proteasome regulatory particle base subunit Rpt6, OB-fold domain [346083] (1 species)
  32. 2451680Proteasome-activating nucleotidase PAN, C-terminal domain [346084] (1 species)
  33. 2451685Rep 40 protein helicase domain [110564] (1 species)
  34. 2451691Replication factor C [64035] (1 species)
    contains additional alpha-helical domain after the family specific domains
  35. 2451699Replication factor C1 [110566] (1 species)
  36. 2451702Replication factor C2 [110572] (1 species)
  37. 2451705Replication factor C3 [110570] (1 species)
  38. 2451708Replication factor C4 [110568] (1 species)
  39. 2451711Replication factor C5 [110574] (1 species)
  40. 2451714Replication protein E1 helicase domain [110576] (1 species)
  41. 2451722Transcriptional activator sigm54 (NtrC1), C-terminal domain [102389] (1 species)
  42. 2451740automated matches [190766] (4 species)
    not a true protein
    1. 2451741Species Aquifex aeolicus [TaxId:63363] [226012] (1 PDB entry)
    2. 2451749Species Human (Homo sapiens) [TaxId:9606] [255867] (6 PDB entries)
    3. 2451784Species Jc polyomavirus [TaxId:10632] [319763] (4 PDB entries)
    4. 2451789Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [187983] (1 PDB entry)

More info for Family c.37.1.20: Extended AAA-ATPase domain

Timeline for Family c.37.1.20: Extended AAA-ATPase domain: